Reaction 21534

Reaction Details
Reaction: Thumb
5-phospho-β-D-ribosylamine + L-glutamate + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + L-glutamine + H2O
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:PRPPAMIDOTRANS-RXN
References:
  • Caskey CT, Ashton DM, Wyngaarden JB (1964). "The enzymology of feedback inhibition of glutamine phosphoribosylpyrophosphate amidotransferase by purine ribonucleotides." J Biol Chem 239;2570-9. PMID: 14235537
  • Hartman SC, Buchanan JM (1958). "Biosynthesis of the purines. XXI. 5-Phosphoribosylpyrophosphate amidotransferase." J Biol Chem 233(2);451-5. PMID: 13563519
  • Tso JY, Hermodson MA, Zalkin H (1982). "Glutamine phosphoribosylpyrophosphate amidotransferase from cloned Escherichia coli purF. NH2-terminal amino acid sequence, identification of the glutamine site, and trace metal analysis." J Biol Chem 257(7);3532-6. PMID: 7037784