Reaction Details
Reaction: Thumb
D-ribose 5-phosphate + ATP = 5-phospho-α-D-ribose 1-diphosphate + AMP + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:PRPPSYN-RXN
References:
  • HUGHES DE, WILLIAMSON DH (1952). "Some properties of the glutaminase of Clostridium welchii." Biochem J 51(1);45-55. PMID: 14944530
  • REMY CN, REMY WT, BUCHANAN JM (1955). "Biosynthesis of the purines. VIII. Enzymatic synthesis and utilization of alpha-5-phosphoribosylpyrophosphate." J Biol Chem 217(2);885-95. PMID: 13271449
  • Switzer RL (1969). "Regulation and mechanism of phosphoribosylpyrophosphate synthetase. I. Purification and properties of the enzyme from Salmonella typhimurium." J Biol Chem 244(11);2854-63. PMID: 4306285