Reaction 21523

Reaction Details
Reaction: Thumb
2-oxo-3-hydroxy-4-phosphobutanoate + L-glutamate → 4-phospho-hydroxy-L-threonine + 2-oxoglutarate
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:PSERTRANSAMPYR-RXN
References:
  • Drewke C, Klein M, Clade D, Arenz A, Muller R, Leistner E (1996). "4-O-phosphoryl-L-threonine, a substrate of the pdxC(serC) gene product involved in vitamin B6 biosynthesis." FEBS Lett 1996;390(2);179-82. PMID: 8706854
  • Hirsch H, Greenberg DM (1967). "Studies on phosphoserine aminotransferase of sheep brain." J Biol Chem 242(9);2283-7. PMID: 6022873
  • Pizer LI (1963). "The pathway and control of serine biosynthesis in Escherichia coli." J Biol Chem 1963;238:3934-3944. PMID: 14086727
  • Zhao G, Winkler ME (1996). "A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduria." J Bacteriol 1996;178(1);232-9. PMID: 8550422
  • Zhao G, Winkler ME (1996). "4-Phospho-hydroxy-L-threonine is an obligatory intermediate in pyridoxal 5'-phosphate coenzyme biosynthesis in Escherichia coli K-12." FEMS Microbiol Lett 1996;135(2-3);275-80. PMID: 8595869