Reaction Details
Reaction: Thumb
D-ribofuranose 5-phosphate + uracil = pseudouridine 5'-phosphate + H2O
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:RXN0-5398
References:
  • Heinrikson RL, Goldwasser E (1964). "Studies on the biosynthesis of 5-ribosyluracil 5'-monophosphate in Tetrahymena pyriformis." J Biol Chem 239;1177-87. PMID: 14165924
  • Matsushita T, Davis FF (1971). "Studies on pseudouridylic acid synthetase from various sources." Biochim Biophys Acta 238(2);165-73. PMID: 4936431
  • Preumont A, Snoussi K, Stroobant V, Collet JF, Van Schaftingen E (2008). "Molecular identification of pseudouridine metabolizing enzymes." J Biol Chem 283(37):25238-46. PMID: 18591240
  • Remsen JF, Matsushita T, Chirikjian JG, Davis FF (1972). "Enzymatic synthesis of deoxypseudouridylic acid and a study of certain of its properties." Biochim Biophys Acta 281(4);481-7. PMID: 4569284
  • Suzuki T, Hochster RM (1966). "On the biosynthesis of pseudouridine and of pseudouridylic acid in Agrobacterium tumefaciens." Can J Biochem 44(2);259-72. PMID: 5942965