Reaction Details
Reaction: Thumb
L-aspartate + L-citrulline + ATP → L-arginino-succinate + AMP + diphosphate + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:ARGSUCCINSYN-RXN
References:
  • Ratner S (1954). "Urea synthesis and metabolism of arginine and citrulline." Adv Enzymol Relat Subj Biochem 15;319-87. PMID: 13158183
  • Schuegraf A, Ratner S, Warner RC (1960). "Free energy changes of the argininosuccinate synthetase reaction and of the hydrolysis of the inner pyrophosphate bond of adenosine triphosphate." J Biol Chem 235;3597-602. PMID: 13748745