Reaction 21482

Reaction Details
Reaction: Thumb
(R)-4'-phosphopantothenate + L-cysteine + CTP → R-4'-phosphopantothenoyl-L-cysteine + CMP + diphosphate + H+
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:P-PANTOCYSLIG-RXN
References:
  • BROWN GM (1959). "The metabolism of pantothenic acid." J Biol Chem 234(2);370-8. PMID: 13630913
  • Kupke T (2002). "Molecular characterization of the 4'-phosphopantothenoylcysteine synthetase domain of bacterial dfp flavoproteins." J Biol Chem 277(39);36137-45. PMID: 12140293
  • Strauss E, Kinsland C, Ge Y, McLafferty FW, Begley TP (2001). "Phosphopantothenoylcysteine synthetase from Escherichia coli. Identification and characterization of the last unidentified coenzyme A biosynthetic enzyme in bacteria." J Biol Chem 276(17);13513-6. PMID: 11278255