Reaction Details
Reaction: Thumb
betaine aldehyde + NAD+ + H2O → glycine betaine + NADH + 2 H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:BADH-RXN
References:
  • Johansson K, El-Ahmad M, Ramaswamy S, Hjelmqvist L, Jornvall H, Eklund H (1998). "Structure of betaine aldehyde dehydrogenase at 2.1 A resolution." Protein Sci 7(10);2106-17. PMID: 9792097
  • Livingstone JR, Maruo T, Yoshida I, Tarui Y, Hirooka K, Yamamoto Y, Tsutui N, Hirasawa E (2003). "Purification and properties of betaine aldehyde dehydrogenase from Avena sativa." J Plant Res 116(2);133-40. PMID: 12736784
  • Munoz-Clares RA, Gonzalez-Segura L, Mujica-Jimenez C, Contreras-Diaz L (2003). "Ligand-induced conformational changes of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa and Amaranthus hypochondriacus L. leaves affecting the reactivity of the catalytic thiol." Chem Biol Interact 143-144;129-37. PMID: 12604197
  • ROTHSCHILD HA, BARRON ES (1954). "The oxidation of betaine aldehyde by betaine aldehyde dehydrogenase." J Biol Chem 209(2);511-23. PMID: 13192104
  • Waditee R, Tanaka Y, Aoki K, Hibino T, Jikuya H, Takano J, Takabe T (2003). "Isolation and functional characterization of N-methyltransferases that catalyze betaine synthesis from glycine in a halotolerant photosynthetic organism Aphanothece halophytica." J Biol Chem 278(7);4932-42. PMID: 12466265