Reaction Details
Reaction: Thumb
D-gluconate 6-phosphate + NADP+ → D-ribulose 5-phosphate + CO2 + NADPH
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:RXN-9952
References:
  • Bridges RB, Palumbo MP, Wittenberger CL (1975). "Purification and properties of an NADP-specific 6-phosphogluconate dehydrogenase from Streptococcus faecalis." J Biol Chem 250(15);6093-100. PMID: 238996
  • Dickens F, Glock GE (1951). "Direct oxidation of glucose-6-phosphate, 6-phosphogluconate and pentose-5-phosphates by enzymes of animal origin." Biochem J 50(1);81-95. PMID: 14904376
  • Pontremoli S, DeFlora A, Grazi E, Mangiarotti G, Bonsignore A, Horecker BL (1961). "Crystalline D-gluconate 6-phosphate dehydrogenase." J Biol Chem 236;2975-80. PMID: 14487824
  • Scott DB, Cohen SS (1953). "The oxidative pathway of carbohydrate metabolism in Escherichia coli. 1. The isolation and properties of glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase." Biochem J 55(1);23-33. PMID: 13093611
  • Scott DB, Cohen SS (1957). "The oxidative pathway of carbohydrate metabolism in Escherichia coli. V. Isolation and identification of ribulose phosphate produced from 6-phosphogluconate by the dehydrogenase of E. coli." Biochem J 65(4);686-9. PMID: 13426085
  • Yoon H, Anderson CD, Anderson BM (1989). "Kinetic studies of Haemophilus influenzae 6-phosphogluconate dehydrogenase." Biochim Biophys Acta 994(1);75-80. PMID: 2783298
  • Zamboni N, Fischer E, Laudert D, Aymerich S, Hohmann HP, Sauer U (2004). "The Bacillus subtilis yqjI gene encodes the NADP+-dependent 6-P-gluconate dehydrogenase in the pentose phosphate pathway." J Bacteriol 186(14);4528-34. PMID: 15231785