Reaction 21470

Reaction Details
Reaction: Thumb
D-glucosamine 1-phosphate + acetyl-CoA → N-acetyl-α-D-glucosamine 1-phosphate + coenzyme A + H+
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:2.3.1.157-RXN
References:
  • Gehring AM, Lees WJ, Mindiola DJ, Walsh CT, Brown ED (1996). "Acetyltransfer precedes uridylyltransfer in the formation of UDP-N-acetylglucosamine in separable active sites of the bifunctional GlmU protein of Escherichia coli." Biochemistry 1996;35(2);579-85. PMID: 8555230
  • Mengin-Lecreulx D, van Heijenoort J (1994). "Copurification of glucosamine-1-phosphate acetyltransferase and N-acetylglucosamine-1-phosphate uridyltransferase activities of Escherichia coli: characterization of the glmU gene product as a bifunctional enzyme catalyzing two subsequent steps in the pathway for UDP-N-acetylglucosamine synthesis." J Bacteriol 176(18);5788-95. PMID: 8083170
  • Olsen LR, Roderick SL (2001). "Structure of the Escherichia coli GlmU pyrophosphorylase and acetyltransferase active sites." Biochemistry 40(7);1913-21. PMID: 11329257