Reaction 21450

Reaction Details
Reaction: Thumb
shikimate + NAD(P)+ ← 3-dehydroshikimate + NAD(P)H + H+
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:RXN-7968
References:
  • Benach J, Lee I, Edstrom W, Kuzin AP, Chiang Y, Acton TB, Montelione GT, Hunt JF (2003). "The 2.3-A crystal structure of the shikimate 5-dehydrogenase orthologue YdiB from Escherichia coli suggests a novel catalytic environment for an NAD-dependent dehydrogenase." J Biol Chem 278(21);19176-82. PMID: 12624088
  • Michel G, Roszak AW, Sauve V, Maclean J, Matte A, Coggins JR, Cygler M, Lapthorn AJ (2003). "Structures of shikimate dehydrogenase AroE and its Paralog YdiB. A common structural framework for different activities." J Biol Chem 278(21);19463-72. PMID: 12637497