Reaction Details
Reaction: Thumb
2-succinylbenzoate + ATP + coenzyme A → 4-(2'-carboxyphenyl)-4-oxobutyryl-CoA + AMP + diphosphate
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:O-SUCCINYLBENZOATE-COA-LIG-RXN
References:
  • Heide L, Arendt S, Leistner E (1982). "Enzymatic synthesis, characterization, and metabolism of the coenzyme A ester of o-succinylbenzoic acid, an intermediate in menaquinone (vitamin K2) biosynthesis." J Biol Chem 1982;257(13);7396-400. PMID: 7045104
  • Kolkmann R, Leistner E "4-(2'-Carboxyphenyl)-4-oxobutyryl coenzyme A ester, an intermediate in vitamin K2 (menaquinone) biosynthesis." Z Naturforsch [C] 42(11-12);1207-14. PMID: 2966501
  • Meganathan R, Bentley R (1979). "Menaquinone (vitamin K2) biosynthesis: conversion of o-succinylbenzoic acid to 1,4-dihydroxy-2-naphthoic acid by Mycobacterium phlei enzymes." J Bacteriol 140(1);92-8. PMID: 500558