Reaction Details
Reaction: Thumb
1,4-dihydroxy-2-naphthoyl-CoA + H2O → 1,4-dihydroxy-2-naphthoate + coenzyme A + H+
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:RXN-9311
References:
  • Chen M, Ma X, Chen X, Jiang M, Song H, Guo Z (2013). "Identification of a Hotdog Fold Thioesterase Involved in the Biosynthesis of Menaquinone in Escherichia coli." J Bacteriol 195(12);2768-75. PMID: 23564174
  • Widhalm JR, van Oostende C, Furt F, Basset GJ (2009). "A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1." Proc Natl Acad Sci U S A 106(14);5599-603. PMID: 19321747