Reaction Details
Reaction: Thumb
isovaleryl-CoA + an oxidized electron-transfer flavoprotein + H+ → 3-methylcrotonyl-CoA + a reduced electron-transfer flavoprotein
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:RXN0-2301
References:
  • BACHHAWAT BK, ROBINSON WG, COON MJ (1956). "Enzymatic carboxylation of beta-hydroxyisovaleryl coenzyme A." J Biol Chem 219(2);539-50. PMID: 13319276
  • Ikeda Y, Tanaka K (1983). "Purification and characterization of isovaleryl coenzyme A dehydrogenase from rat liver mitochondria." J Biol Chem 258(2);1077-85. PMID: 6401713
  • Tanaka K, Budd MA, Efron ML, Isselbacher KJ (1966). "Isovaleric acidemia: a new genetic defect of leucine metabolism." Proc Natl Acad Sci U S A 56(1);236-42. PMID: 5229850