Reaction Details
Reaction: Thumb
ATP + N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + L-glutamine + H2O → L-glutamate + ADP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine + phosphate + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:FGAMSYN-RXN
References:
  • MELNICK I, BUCHANAN JM (1957). "Biosynthesis of the purines. XIV. Conversion of (alpha-N-formyl) glycinamide ribotide to (alpha-N-formyl) glycinamidine ribotide; purification and requirements of the enzyme system." J Biol Chem 225(1);157-62. PMID: 13416226