Reaction 21341

Reaction Details
Reaction: Thumb
CO2 + β-nicotinate D-ribonucleotide + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + quinolinate + 2 H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:QUINOPRIBOTRANS-RXN
References:
  • GHOLSON RK, UEDA I, OGASAWARA N, HENDERSON LM (1964). "THE ENZYMATIC CONVERSION OF QUINOLINATE TO NICOTINIC ACID MONONUCLEOTIDE IN MAMMALIAN LIVER." J Biol Chem 239;1208-14. PMID: 14165928
  • Katoh A, Uenohara K, Akita M, Hashimoto T (2006). "Early steps in the biosynthesis of NAD in Arabidopsis start with aspartate and occur in the plastid." Plant Physiol 141(3);851-7. PMID: 16698895
  • Packman PM, Jakoby WB (1965). "Crystalline quinolinate phosphoribosyltransferase." J Biol Chem 240(10);4107-8. PMID: 5320648