Reaction 21330

Reaction Details
Reaction: Thumb
precorrin-5 + S-adenosyl-L-methionine + H2O → precorrin-6A + S-adenosyl-L-homocysteine + acetate + 2 H+
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:R322-RXN
References:
  • Debussche L, Thibaut D, Cameron B, Crouzet J, Blanche F (1993). "Biosynthesis of the corrin macrocycle of coenzyme B12 in Pseudomonas denitrificans." J Bacteriol 175(22);7430-40. PMID: 8226690
  • Warren MJ, Raux E, Schubert HL, Escalante-Semerena JC (2002). "The biosynthesis of adenosylcobalamin (vitamin B12)." Nat Prod Rep 19(4);390-412. PMID: 12195810