Reaction 21329

Reaction Details
Reaction: Thumb
hydrogenobyrinate + 2 L-glutamine + 2 ATP + 2 H2O → 2 L-glutamate + hydrogenobyrinate a,c-diamide + 2 ADP + 2 phosphate + 2 H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:R341-RXN
References:
  • Debussche L, Thibaut D, Cameron B, Crouzet J, Blanche F (1990). "Purification and characterization of cobyrinic acid a,c-diamide synthase from Pseudomonas denitrificans." J Bacteriol 1990;172(11);6239-44. PMID: 2172209
  • Warren MJ, Raux E, Schubert HL, Escalante-Semerena JC (2002). "The biosynthesis of adenosylcobalamin (vitamin B12)." Nat Prod Rep 19(4);390-412. PMID: 12195810