Reaction Details
Reaction: Thumb
decanoyl-CoA + an oxidized electron-transfer flavoprotein + H+ → trans-Δ2-decenoyl-CoA + a reduced electron-transfer flavoprotein
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:RXN-13615
References:
  • Crane FL, Hauge JG, Beinert H (1955). "Flavoproteins involved in the first oxidative step of the fatty acid cycle." Biochim Biophys Acta 17(2);292-4. PMID: 13239683
  • Crane FL, Mii S, Hauge JG, Green DE, Beinert H (1956). "On the mechanism of dehydrogenation of fatty acyl derivatives of coenzyme A. I. The general fatty acyl coenzyme A dehydrogenase." J Biol Chem 218(2);701-6. PMID: 13295224
  • Ikeda Y, Okamura-Ikeda K, Tanaka K (1985). "Purification and characterization of short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria. Isolation of the holo- and apoenzymes and conversion of the apoenzyme to the holoenzyme." J Biol Chem 260(2);1311-25. PMID: 3968063
  • Kim JJ, Wang M, Paschke R (1993). "Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate." Proc Natl Acad Sci U S A 90(16);7523-7. PMID: 8356049
  • Peterson KL, Sergienko EE, Wu Y, Kumar NR, Strauss AW, Oleson AE, Muhonen WW, Shabb JB, Srivastava DK (1995). "Recombinant human liver medium-chain acyl-CoA dehydrogenase: purification, characterization, and the mechanism of interactions with functionally diverse C8-CoA molecules." Biochemistry 34(45);14942-53. PMID: 7578106
  • Thorpe C, Kim JJ (1995). "Structure and mechanism of action of the acyl-CoA dehydrogenases." FASEB J 9(9);718-25. PMID: 7601336
  • Toogood HS, van Thiel A, Basran J, Sutcliffe MJ, Scrutton NS, Leys D (2004). "Extensive domain motion and electron transfer in the human electron transferring flavoprotein.medium chain Acyl-CoA dehydrogenase complex." J Biol Chem 279(31);32904-12. PMID: 15159392