Reaction 21295

Reaction Details
Reaction: Thumb
1-pyrroline-4-hydroxy-2-carboxylate + H+ + H2O → ammonium + 2,5-dioxopentanoate
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:3.5.4.22-RXN
References:
  • Singh RM, Adams E (1965). "Enzymatic deamination of delta-1-pyrroline-4-hydroxy-2-carboxylate to 2,5-dioxovalerate (alpha-ketoglutaric semialdehyde)." J Biol Chem 240(11);4344-51. PMID: 5845838
  • Singh RM, Adams E (1965). "Isolation and identification of 2,5-dioxovalerate, an intermediate in the bacterial oxidation of hydroxyproline." J Biol Chem 240(11);4352-6. PMID: 5845839