Reaction Details
Reaction: Thumb
2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ → 5-amino-6-(D-ribitylamino)uracil + riboflavin
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:RIBOFLAVIN-SYN-RXN
References:
  • PLAUT GW (1963). "Studies on the nature of the enzymic conversion of 6,7-dimethyl-8-ribityllumazine to riboflavin." J Biol Chem 238;2225-43. PMID: 13944007
  • WACKER H, HARVEY RA, WINESTOCK CH, PLAUT GW (1964). "4-(1'-D-RIBITYLAMINO)-5-AMINO-2,6-DIHYDROXYPYRIMIDINE, THE SECOND PRODUCT OF THE RIBOFLAVIN SYNTHETASE REACTION." J Biol Chem 239;3493-7. PMID: 14245407