Reaction Details
Reaction: Thumb
shikimate + NADP+ ← 3-dehydroshikimate + NADPH + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:SHIKIMATE-5-DEHYDROGENASE-RXN
References:
  • Anton IA, Coggins JR (1988). "Sequencing and overexpression of the Escherichia coli aroE gene encoding shikimate dehydrogenase." Biochem J 249(2);319-26. PMID: 3277621
  • BALINSKY D, DAVIES DD (1961). "Aromatic biosynthesis in higher plants. 1. Preparation and properties of dehydroshikimic reductase." Biochem J 80;292-6. PMID: 13686342
  • Chaudhuri S, Coggins JR (1985). "The purification of shikimate dehydrogenase from Escherichia coli." Biochem J 1985;226(1);217-23. PMID: 3883995
  • MITSUHASHI S, DAVIS BD (1954). "Aromatic biosynthesis. XIII. Conversion of quinic acid to 5-dehydroquinic acid by quinic dehydrogenase." Biochim Biophys Acta 15(2);268-80. PMID: 13208693
  • YANIV H, GILVARG C (1955). "Aromatic biosynthesis. XIV. 5-Dehydroshikimic reductase." J Biol Chem 213(2);787-95. PMID: 14367339
  • Ye S, Von Delft F, Brooun A, Knuth MW, Swanson RV, McRee DE (2003). "The crystal structure of shikimate dehydrogenase (AroE) reveals a unique NADPH binding mode." J Bacteriol 185(14);4144-51. PMID: 12837789