Reaction Details
Reaction: Thumb
spermidine + S-adenosyl 3-(methylthio)propylamine → spermine + S-methyl-5'-thioadenosine + H+
Enzymes: Not Available
External Links:
ResourceLink
PseudoCyc Reaction ID:SPERMINE-SYNTHASE-RXN
References:
  • Hibasami H, Borchardt RT, Chen SY, Coward JK, Pegg AE (1980). "Studies of inhibition of rat spermidine synthase and spermine synthase." Biochem J 187(2);419-28. PMID: 7396856
  • Pajula RL, Raina A, Eloranta T (1979). "Polyamine synthesis in mammalian tissues. Isolation and characterization of spermine synthase from bovine brain." Eur J Biochem 101(2);619-26. PMID: 520313
  • Pegg AE, Shuttleworth K, Hibasami H (1981). "Specificity of mammalian spermidine synthase and spermine synthase." Biochem J 197(2);315-20. PMID: 6798961