Reaction Details
Reaction: Thumb
chloramphenicol + acetyl-CoA = chloramphenicol 3-acetate + chloramphenicol 3-acetate + coenzyme A
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:CHLORAMPHENICOL-O-ACETYLTRANSFERASE-RXN
References:
  • Shaw WV (1967). "The enzymatic acetylation of chloramphenicol by extracts of R factor-resistant Escherichia coli." J Biol Chem 242(4);687-93. PMID: 5335032
  • Shaw WV, Brodsky RF (1968). "Characterization of chloramphenicol acetyltransferase from chloramphenicol-resistant Staphylococcus aureus." J Bacteriol 95(1);28-36. PMID: 4965980