Diaminopimelate epimerase (PA5278)

Identification
Name: Diaminopimelate epimerase
Synonyms:
  • DAP epimerase
Gene Name: dapF
Enzyme Class:
Biological Properties
General Function: Involved in diaminopimelate epimerase activity
Specific Function: LL-2,6-diaminoheptanedioate = meso- diaminoheptanedioate
Cellular Location: Cytoplasm
KEGG Pathways:
Transports:
Transport References:
  • Orth, J. D., Conrad, T. M., Na, J., Lerman, J. A., Nam, H., Feist, A. M., Palsson, B. O. (2011). "A comprehensive genome-scale reconstruction of Escherichia coli metabolism--2011." Mol Syst Biol 7:535. Pubmed: 21988831
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb ↔ Thumb
Diaminopimelic acid ↔ Meso-2,6-Diaminoheptanedioate
ReactionCard
Thumb ↔ meso-diaminopimelate
Diaminopimelic acid ↔ meso-diaminopimelate
ReactionCard
Thumb
L,L-diaminopimelate → meso-diaminopimelate
ReactionCard
Complex Reactions: Not Available
Transports:
Metabolites:
PAMDB IDNameView
PAMDB000360Diaminopimelic acidMetaboCard
PAMDB002055Meso-2,6-DiaminoheptanedioateMetaboCard
GO Classification:
Component
cell part
cytoplasm
intracellular part
Function
amino-acid racemase activity
catalytic activity
diaminopimelate epimerase activity
isomerase activity
racemase and epimerase activity
racemase and epimerase activity, acting on amino acids and derivatives
Process
aspartate family amino acid metabolic process
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process
cellular metabolic process
lysine biosynthetic process
lysine biosynthetic process via diaminopimelate
lysine metabolic process
metabolic process
Gene Properties
Locus tag: PA5278
Strand: +
Entrez Gene ID: 877750
Accession: NP_253965.1
GI: 15600471
Sequence start: 5942745
Sequence End: 5943575
Sequence Length: 830
Gene Sequence: 
>PA5278
ATGCTTTTGCGCTTCACCAAGATGCATGGCCTGGGCAACGACTTCATGGTCCTCGACCTGGTCAGCCAGCACGCCCATGTGCAGCCCAAGCACGTCAAGCTCTGGGGCGACCGCAACACCGGAATCGGCTTCGACCAGTTGCTGATCGTCGAAGCCCCGAGCAGCCCCGACGTCGACTTCCGCTACCGGATCTTCAACGCCGACGGCTCCGAGGTCGAGCAGTGCGGCAACGGCGCTCGCTGCTTCGCCCGCTTCGTTCAGGACAAGCGCCTGACGGTGAAGAAGAGCATCCGCGTAGAAACCAAGGGCGGCATCATCGAGCTGAATATCCGCCCGGACGGCCAGGTCACGGTGGACATGGGTCCGCCGCGCCTGGCCCCGGCCGAGATACCGTTCCAGGCCGAGCGCGAAGCCTTGTCCTATGAGATAGAGGTGAATGGCCAGCGCGTCGAACTGGCCGCGGTATCCATGGGCAATCCCCATGGCGTGCTGCGCGTCGAGAACGTCGACAGCGCACCGGTACACAGCCTCGGTCCGCAACTGGAAGTCCATCCGCGCTTCCCGAAGAAGGCCAACATCGGCTTCCTCCAGGTGCTCGATCCGCACCATGCGCGCCTGCGCGTCTGGGAGCGCGGCGTCGGCGAGACCCAAGCCTGCGGCACCGGCGCCTGCGCCGCGGCGGTTGCCGGGATTCGCCAGGGCTGGCTGCAATCGCCGGTGCAGATCGACCTCCCCGGCGGCCGCCTGCACATCGAGTGGGCAGGTCCCGGCCAGCCCGTTATGATGACCGGGCCTGCCGTCCGCGTGTATGAAGGCCAGGTCCGCCTGTAA
Protein Properties
Protein Residues: 276
Protein Molecular Weight: 30.3 kDa
Protein Theoretical pI: 7.67
Hydropathicity (GRAVY score): -0.212
Charge at pH 7 (predicted): 2.28
Protein Sequence: 
>PA5278
MLLRFTKMHGLGNDFMVLDLVSQHAHVQPKHVKLWGDRNTGIGFDQLLIVEAPSSPDVDFRYRIFNADGSEVEQCGNGARCFARFVQDKRLTVKKSIRVETKGGIIELNIRPDGQVTVDMGPPRLAPAEIPFQAEREALSYEIEVNGQRVELAAVSMGNPHGVLRVENVDSAPVHSLGPQLEVHPRFPKKANIGFLQVLDPHHARLRVWERGVGETQACGTGACAAAVAGIRQGWLQSPVQIDLPGGRLHIEWAGPGQPVMMTGPAVRVYEGQVRL
References
External Links:
Resource Link
Genome ID: PA5278
Entrez Gene ID: 877750
NCBI Protein ID: 15600471
General Reference: PaperBLAST - Find papers about PA5278 and its homologs