P. aeruginosa Metabolome Database Protein PA5067

Identification

Name:

phosphoribosyl-ATP pyrophosphohydrolase

Synonyms:

Not Available

Gene Name:

hisE

Enzyme Class:

Not Available

Biological Properties

General Function:

histidine biosynthetic process

Specific Function:

phosphoribosyl-ATP diphosphatase activity

Cellular Location:

Cytoplasmic

KEGG Pathways:

superpathway of histidine, purine, and pyrimidine biosynthesis PRPP-PWY
L-histidine biosynthesis HISTSYN-PWY

KEGG Reactions:

Not Available

SMPDB Reactions:

Not Available

PseudoCyc/BioCyc Reactions:

1-(5-phospho-β-D-ribosyl)-ATP + H₂O → 1-(5-phospho-β-D-ribosyl)-AMP + diphosphate + 2 H⁺
ReactionCard

Complex Reactions:

Not Available

Transports:

Not Available

Metabolites:

Not Available

GO Classification:

Function
phosphoribosyl-ATP diphosphatase activity
Process
histidine biosynthetic process

Gene Properties

Locus tag:

PA5067

Strand:

Entrez Gene ID:

878486

Accession:

NP_253754.1

GI:

15600260

Sequence start:

5706191

Sequence End:

5706526

Sequence Length:

335

Gene Sequence:

>PA5067
ATGAGTGACACCCTGACCCGCCTGGCGGCGGTGCTCGAGGAGCGCAAGAACGCCGCGCCCGACAGCTCCTACGTGGCCAGTCTGTACCACAAAGGCCTGAACAAGATCCTGGAGAAGGTCGGCGAGGAGTCGGTGGAAACCATCATCGCCGCCAAGGATGCCGCGGCCAGCGGCGACTGCCAGGACCTGATCTACGAAACCGCCGACCTCTGGTTCCACTCGCTGGTGATGCTCTCGGCCCTCGGCCAGCATCCGCAAGCCGTGCTGGACGAACTGGAGCGCCGCTTCGGCCTTTCCGGCCACGCCGAGAAAGCCGCCCGCCAACCATCGGCCTGA

Protein Properties

Protein Residues:

111

Protein Molecular Weight:

12 kDa

Protein Theoretical pI:

4.89

Hydropathicity (GRAVY score):

-0.208

Charge at pH 7 (predicted):

-5.08

Protein Sequence:

>PA5067
MSDTLTRLAAVLEERKNAAPDSSYVASLYHKGLNKILEKVGEESVETIIAAKDAAASGDCQDLIYETADLWFHSLVMLSALGQHPQAVLDELERRFGLSGHAEKAARQPSA

References

External Links:

Resource	Link
Genome ID:	PA5067
Entrez Gene ID:	878486
NCBI Protein ID:	15600260

General Reference:

PaperBLAST - Find papers about PA5067 and its homologs

phosphoribosyl-ATP pyrophosphohydrolase (PA5067)