Glutamate-ammonia-ligase adenylyltransferase (PA5014)

Identification
Name: Glutamate-ammonia-ligase adenylyltransferase
Synonyms:
  • Glutamine-synthetase adenylyltransferase
  • ATase
  • [Glutamate--ammonia-ligase] adenylyltransferase
Gene Name: glnE
Enzyme Class:
Biological Properties
General Function: Involved in [glutamate-ammonia-ligase] adenylyltransferase activity
Specific Function: Adenylation and deadenylation of glutamate--ammonia ligase
Cellular Location: Not Available
KEGG Pathways: Not Available
KEGG Reactions:
Thumb ↔ Thumb
Adenosine triphosphate ↔ Pyrophosphate
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+[L-glutamate:ammonia ligase (ADP-forming)] → Thumb+adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]
Adenosine triphosphate + [L-glutamate:ammonia ligase (ADP-forming)] → Pyrophosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]
ReactionCard
Thumb ↔ Thumb
Adenosine triphosphate ↔ Pyrophosphate
ReactionCard
Thumb
a [glutamine-synthetase]-L-tyrosine + ATP = a [glutamine synthetase]-O4-(5'-adenylyl)-L-tyrosine + diphosphate
ReactionCard
Complex Reactions:
Thumb+[L-glutamate:ammonia ligase (ADP-forming)] → Thumb+adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]
Adenosine triphosphate + [L-glutamate:ammonia ligase (ADP-forming)] → Pyrophosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000633PyrophosphateMetaboCard
GO Classification:
Function
adenylyltransferase activity
catalytic activity
nucleotidyltransferase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
[glutamate-ammonia-ligase] adenylyltransferase activity
Gene Properties
Locus tag: PA5014
Strand: -
Entrez Gene ID: 881325
Accession: NP_253701.1
GI: 15600207
Sequence start: 5632926
Sequence End: 5635874
Sequence Length: 2948
Gene Sequence: 
>PA5014
ATGAGCCTGCCTTCGCTGGCGAATCTGCCGGCCACCCTGCTGCCCGCCGCCGAACGCGCCGGGACTGCCCTCCGCTCCGCTGTCGCCGCCCTCGATGCCGCCGCCCTGGCCCGCCTGGAGGCCTGGCCCGAGGAGCGCCTGGAGGATTTCCGACGGGTCGCCGCGGCCAGCGATTTCGTCGCCGAGCAGGCAGTGCGCGACTCGGCGATGCTGCTGGAACTGGCCGAACGCGGCGAGCTGGAGAACCCCCACGCGCCCGGCGAACTGCGCAGTCAGTTGCAGGCGCGGCTGGAGGATTGCGCCGACGAGGACGAACTCGGTCGGCGCCTGCGACGTTTCCGCACACGCCAGCAACTGCGCATCATCTGGCGCGACCTGACCCGCCGCGCCGCGCTGGCGGAAACCTGTCGCGACCTGTCGGCCCTGGCCGACGCCTGCATCGACCTGGCTTGCGAGTGGCTCCATCGGCGCCAGTGCGAGCAGTTCGGCACGCCGATCGGCCGGCGCTCCGGCGAACCGCAGCGGATGGTGGTCCTCGGCATGGGCAAGCTGGGCGCGGTGGAACTCAACCTGTCGTCGGACATCGACCTGATCTTCGGTTACCCGGAGGGCGGCGAGACCGAGGGGGCGAAGCGTTCGCTGGACAACCAGGAGTTCTTCACCCGCTTGGGGCAGAAGCTGATCAAGGCGCTGGATGCGATCACCGTCGACGGCTTCGTCTTCCGCGTCGACATGCGCCTGCGTCCCTACGGCTCCAGCGGACCGCTGGTCTACAGCTTCGCCGCGCTGGAGCAGTACTACCAGGACCAGGGGCGCGACTGGGAGCGCTACGCGATGATCAAGGCGCGGGTGGTCGGCGGCGACCAGCAGGCAGGCGAGCAACTGCTCGGCATGCTGCGGCCGTTCGTCTATCGGCGCTACCTGGACTTTTCCGCCATCGAGGCGCTGCGCACCATGAAGCAGCTGATCCAGCAGGAGGTCCGGCGCAAGGGGATGTCGGAAAACATCAAGCTGGGCGAAGGCGGTATCCGCGAGGTGGAGTTCATCGCCCAGGCCTTCCAGTTGATCCATGGCGGGCGCGACCTGAGCTTGCAGCAACGGCCGCTGCTGAAGGTGCTGGCGACCCTGGAGGGGCAGGGCTACCTGCCGCCGGCGGTGGTCGAGGAGCTGCGCGGCGGCTACGAGTTCCTGCGCTACGCCGAGCATGCCATCCAGGCGCTGGCCGACCGGCAGACGCAAATGCTGCCCAGCGACGAATACGACCGCATCCGCGTGGCCTTCATCATGGGCTTCGCCAGTTGGGCCGCATTCCACGAGCGCCTGAGCCACTGGCGGGCGCGCATCGACTGGCACTTCCGCCAGGTGATCGCCGACCCGGACGAGGACGAAAGCGGCGAGGCGGCCTGCGGCAGCGTCGGCGCCGAGTGGATCCCGCTGTGGGAGGAGGCGCTGGACGAGGAGTCGGCCAGCCGGCAACTGGCCGACGCCGGCTTCGTCGATGCCGAGGCGGCCTGGAAGCGTCTCAGCGATCTGCGCCACGGCCCCCAGGTACGAGCGATGCAGCGTCTCGGCCGGGAGCGCCTGGATGCCTTCGTTCCGCGCCTGCTGGCGATGACCGTGGAAAACCCCCAGCCGGACCTGGTGCTGGAGCGGGTCCTGCCGCTGGTGGAAGCGGTGGCGCGGCGTTCCGCCTACCTGGTGTTGCTGACCGAGAACCCCGGCGCGCTGGAGCGCCTGCTGACCCTCTGCGCGGCCAGCCCGATGGTTGCCGAGCAGATCGCGCGGTTCCCGATTCTGCTCGACGAGCTGCTCAACGAGGGGCGCCTGTTCCGTCCTCCACAGGCCGCCGAGCTGGCCGCCGAGCTGCGCGAACGGCTGATGCGGATTCCCGAGGACGACCTCGAGCAGCAGATGGAGACCCTTCGTCACTTCAAGCTGGCCCACGGGCTGCGGGTGGCGGCCTCGGAGATCGCCGGCACGCTGCCGTTGATGAAGGTCAGCGACTACCTGACCTGGCTGGCCGAGGCGATCCTCGTCGAGGTCCTCGAACTGGCCTGGCGGCAGTTGGTGCAGCGTCACGGCCGGCCGTTGCGCGCCGACGGCACGCCGTGCGATCCGGACTTCGTCATCGTCGGCTACGGCAAGGTCGGCGGGCTGGAGTTCGGCCATGGCTCGGACCTCGACCTGGTGTTCATCCATGACGGCGACCCCCAGTGCGAGACCGATGGCGGCAAATCCATCGATGGCGCGCAGTTCTTTACCCGCCTGGGGCAGAAGATCATCCATTTCCTCACCGCGCAGACGCCATCCGGCACCCTCTACGAGGTCGACATGCGCCTGCGTCCGAGCGGCGCGGCCGGCCTGCTGGTGAGTTCGCTGGGCGCCTTCCAGCGCTACCAGGAGCAGGAGGCCTGGACCTGGGAGCACCAGGCGTTGGTCCGCGCCCGGGTGCTGGCCGGTTGCCGGCGGGTGCAGGCGAGCTTCGAGGCGGTACGTGCCGAGGTGCTGGCGAGGCCGCGCGATCTCGACGCGTTGCGCACCGAAGTCAGCGAAATGCGCGCCAAGATGCGCGACAACCTGGGAACCCGCGCGACCGCCGCCGGTACCGCCTCGAATGCCTTCGAGGCCACGGCAGCCTTCGATCTCAAGCACGATGCCGGTGGTATCGTCGATATCGAATTTATGGTGCAATATGCGGTTCTAGCTTGGTCCGGAGAACACCCGGCGCTGCTCGAATTCACCGATAACATCCGCATTCTGGAAGGACTGGAACGGGCTGGCCTGATCGCCAGCGAGGACGTCCGTCTCCTGCAGGAGGCCTACAAGGCCTATCGCGCAGCCGCACACCGCCTGGCACTACAGAAGGAGGCCGGGGTCGTGAGCGGCGAGCACTTCCAGACGGAGCGGCGAGAAGTGATCAGGATCTGGCGCGAGCTGCGGCTCGGCTGA
Protein Properties
Protein Residues: 982
Protein Molecular Weight: 110.1 kDa
Protein Theoretical pI: 5.22
Hydropathicity (GRAVY score): -0.224
Charge at pH 7 (predicted): -22.63
Protein Sequence: 
>PA5014
MSLPSLANLPATLLPAAERAGTALRSAVAALDAAALARLEAWPEERLEDFRRVAAASDFVAEQAVRDSAMLLELAERGELENPHAPGELRSQLQARLEDCADEDELGRRLRRFRTRQQLRIIWRDLTRRAALAETCRDLSALADACIDLACEWLHRRQCEQFGTPIGRRSGEPQRMVVLGMGKLGAVELNLSSDIDLIFGYPEGGETEGAKRSLDNQEFFTRLGQKLIKALDAITVDGFVFRVDMRLRPYGSSGPLVYSFAALEQYYQDQGRDWERYAMIKARVVGGDQQAGEQLLGMLRPFVYRRYLDFSAIEALRTMKQLIQQEVRRKGMSENIKLGEGGIREVEFIAQAFQLIHGGRDLSLQQRPLLKVLATLEGQGYLPPAVVEELRGGYEFLRYAEHAIQALADRQTQMLPSDEYDRIRVAFIMGFASWAAFHERLSHWRARIDWHFRQVIADPDEDESGEAACGSVGAEWIPLWEEALDEESASRQLADAGFVDAEAAWKRLSDLRHGPQVRAMQRLGRERLDAFVPRLLAMTVENPQPDLVLERVLPLVEAVARRSAYLVLLTENPGALERLLTLCAASPMVAEQIARFPILLDELLNEGRLFRPPQAAELAAELRERLMRIPEDDLEQQMETLRHFKLAHGLRVAASEIAGTLPLMKVSDYLTWLAEAILVEVLELAWRQLVQRHGRPLRADGTPCDPDFVIVGYGKVGGLEFGHGSDLDLVFIHDGDPQCETDGGKSIDGAQFFTRLGQKIIHFLTAQTPSGTLYEVDMRLRPSGAAGLLVSSLGAFQRYQEQEAWTWEHQALVRARVLAGCRRVQASFEAVRAEVLARPRDLDALRTEVSEMRAKMRDNLGTRATAAGTASNAFEATAAFDLKHDAGGIVDIEFMVQYAVLAWSGEHPALLEFTDNIRILEGLERAGLIASEDVRLLQEAYKAYRAAAHRLALQKEAGVVSGEHFQTERREVIRIWRELRLG
References
External Links:
Resource Link
Genome ID: PA5014
Entrez Gene ID: 881325
NCBI Protein ID: 15600207
General Reference: PaperBLAST - Find papers about PA5014 and its homologs