tRNA dimethylallyltransferase (PA4945)

Identification
Name: tRNA dimethylallyltransferase
Synonyms:
  • Dimethylallyl diphosphate:tRNA dimethylallyltransferase
  • DMAPP:tRNA dimethylallyltransferase
  • DMATase
  • Isopentenyl-diphosphate:tRNA isopentenyltransferase
  • IPP transferase
  • IPPT
  • IPTase
Gene Name: miaA
Enzyme Class:
Biological Properties
General Function: Involved in ATP binding
Specific Function: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+tRNA ↔ Thumb+tRNA containing 6-isopentenyladenosine
Dimethylallylpyrophosphate + tRNA ↔ Pyrophosphate + tRNA containing 6-isopentenyladenosine
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+tRNA ↔ Thumb+tRNA containing 6-isopentenyladenosine
Dimethylallylpyrophosphate + tRNA ↔ Pyrophosphate + tRNA containing 6-isopentenyladenosine
ReactionCard
Thumb+tRNA → Thumb+tRNA containing 6-dimethylallyladenosine
Dimethylallylpyrophosphate + tRNA → Pyrophosphate + tRNA containing 6-dimethylallyladenosine
ReactionCard
Thumb
dimethylallyl diphosphate + an adenosine37 in tRNA = N6-dimethylallyladenosine37 in tRNA + diphosphate
ReactionCard
Complex Reactions:
Thumb+tRNA → Thumb+tRNA containing 6-dimethylallyladenosine
Dimethylallylpyrophosphate + tRNA → Pyrophosphate + tRNA containing 6-dimethylallyladenosine
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000260DimethylallylpyrophosphateMetaboCard
PAMDB000633PyrophosphateMetaboCard
GO Classification:
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
ATP binding
binding
nucleoside binding
purine nucleoside binding
Process
cellular macromolecule metabolic process
macromolecule metabolic process
metabolic process
ncRNA metabolic process
RNA metabolic process
tRNA metabolic process
tRNA processing
Gene Properties
Locus tag: PA4945
Strand: -
Entrez Gene ID: 878016
Accession: NP_253632.1
GI: 15600138
Sequence start: 5548751
Sequence End: 5549722
Sequence Length: 971
Gene Sequence: 
>PA4945
ATGTCTTCCCTGCCTCCCGCCATCTTTCTCATGGGGCCGACCGCCGCCGGCAAGACCGACCTGGCGATGGCGCTGGCCGATGCGCTGCCCTGCGAGCTGATCAGCGTCGACTCGGCGCTGATCTACCGCGGTATGGATATCGGTACGGCCAAGCCTTCCCGGGAGCTGCTGGCGCGCTATCCGCACCGCCTGATCGATATCCGCGACCCGGCGGAGAGCTATTCGGCCGCGGAATTTCGCGCCGACGCCCTGGCGGCGATGGCCAAGGCCACCGCGCGCGGCAGGATTCCCCTGCTGGTGGGGGGCACCATGCTCTATTACAAGGCGTTGCTCGAGGGCCTGGCCGACATGCCCGGCGCCGATCCCGAGGTGCGCGCGGCGATCGAGGCCGAGGCCCAGGCCGAAGGTTGGGAGGCGCTGCACCGGCAACTCGCCGAGGTCGACCCGGAATCGGCTGCGCGTATCCACCCCAACGACCCGCAGCGACTGATGCGGGCGCTCGAGGTGTATCGCCTCGGCGGGGTGTCGATGAGCGACCTGCGTCGCCGGCAAAGCGCTGAAAAGGCGGATTTTGACGCGTCAGGCAGGAATCAATTGCCGTATACTGTCGCTCAGCTGGCGATTGCTCCCGAGCAGCGCCAGGTGTTGCACGCGCGGATTGCGCAGCGTTTTCGCCAGATGCTGGAACAGGGTTTCATCGCCGAGGTCGAAGCACTGCATGCCAGAAGTGACTTGCATGCAGGATTACCGTCTATTAGAGCCGTGGGTTACCGTCAGGTGTGGGATTACCTGGATGGCAAGCTGTCCTACGCTGAAATGACCGAGCGCGGCATCATCGCTACCCGCCAGTTGGCCAAGCGCCAGTTCACCTGGCTGCGAAGCTGGAGCCATCTACACTGGATGGACAGCCTAGCAGGTGACAATCTGCCGCGTGCCTTGAAATACCTGAAAACGGTCTCCATATTGGCCTGA
Protein Properties
Protein Residues: 323
Protein Molecular Weight: 35.8 kDa
Protein Theoretical pI: 7.81
Hydropathicity (GRAVY score): -0.178
Charge at pH 7 (predicted): 1.9
Protein Sequence: 
>PA4945
MSSLPPAIFLMGPTAAGKTDLAMALADALPCELISVDSALIYRGMDIGTAKPSRELLARYPHRLIDIRDPAESYSAAEFRADALAAMAKATARGRIPLLVGGTMLYYKALLEGLADMPGADPEVRAAIEAEAQAEGWEALHRQLAEVDPESAARIHPNDPQRLMRALEVYRLGGVSMSDLRRRQSAEKADFDASGRNQLPYTVAQLAIAPEQRQVLHARIAQRFRQMLEQGFIAEVEALHARSDLHAGLPSIRAVGYRQVWDYLDGKLSYAEMTERGIIATRQLAKRQFTWLRSWSHLHWMDSLAGDNLPRALKYLKTVSILA
References
External Links:
Resource Link
Genome ID: PA4945
Entrez Gene ID: 878016
NCBI Protein ID: 15600138
General Reference: PaperBLAST - Find papers about PA4945 and its homologs