Identification |
Name: |
5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase |
Synonyms: |
hpaE |
Gene Name: |
hpcC |
Enzyme Class: |
Not Available |
Biological Properties |
General Function: |
carbon utilization, 4-hydroxyphenylacetate metabolic process, cellular catabolic process, metabolic process, oxidation-reduction process, 4-hydroxyphenylacetate catabolic process |
Specific Function: |
oxidoreductase activity, 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
Cellular Location: |
Cytoplasmic |
KEGG Pathways: |
|
KEGG Reactions: |
Not Available |
SMPDB Reactions: |
Not Available |
PseudoCyc/BioCyc Reactions: |
| 2-hydroxy-5-carboxymethylmuconate semialdehyde + NAD + + H 2O → 5-carboxymethyl-2-hydroxymuconate + NADH + 2 H +ReactionCard |
|
Complex Reactions: |
Not Available |
Transports: |
Not Available |
Metabolites: |
Not Available |
GO Classification: |
Function |
---|
oxidoreductase activity | 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | Process |
---|
carbon utilization | 4-hydroxyphenylacetate metabolic process | cellular catabolic process | metabolic process | oxidation-reduction process | 4-hydroxyphenylacetate catabolic process |
|
Gene Properties |
Locus tag: |
PA4123 |
Strand: |
+ |
Entrez Gene ID: |
880100 |
Accession: |
NP_252812.1 |
GI: |
15599318 |
Sequence start: |
4611013 |
Sequence End: |
4612473 |
Sequence Length: |
1460 |
Gene Sequence: |
>PA4123
ATGATCAAACACTGGATCAATGGCCGCGAGGTCGAAAGCAAGGACGTCTTCGAGAACTACAACCCGGCCACCGGCGAGCTGATCGGCGAGGTCGCCAGCGGCGGCGCGGCGGAAATCGACGCGGCGGTGGCGGCGGCCCGGGAAGCCTTCCCGAAATGGGCCAATACCCCGGCCAAGGAGCGCGCGCGCCTGATGCGCCGGCTCGGCGAGCTGATCGACCGGAACGTGCCGCACCTGGCGGAACTTGAGACCCTCGACACCGGCCTGCCGATCCACCAGACGAAGAACGTGCTGATCCCGCGCGCCTCGCACAACTTCGAGTTCTTCGCCGAAGTCTGCACGCGGATGAACGGGCACAGCTATCCGGTCGACGACCAGATGCTCAACTACACCCTGTACCAGCCGGTAGGCGTCTGCGGCCTGGTCTCGCCGTGGAACGTACCGTTCATGACCGCCACCTGGAAGACCGCGCCGTGCCTGGCGCTGGGCAACACGGCGGTGCTGAAGATGTCCGAGCTGTCGCCGCTGACCGCCAACGAGCTGGGCCGCCTGGTGCACGAGGCGGGCATTCCGCCGGGGGTGTTCAACGTGGTCCAGGGCTACGGCGCCAGCGCCGGCGACGCGCTGGTTCGCCACCGCGACGTGCGCGCGGTGTCCTTCACCGGCGGCACCGCCACCGGGCGACGGATCATGGAGGCGGCCGGGATCAAGAAATACTCGATGGAACTGGGCGGCAAGTCGCCGGTGCTGGTCTTCGAAGACGCCGACCTCGAGCGGGCGCTGGACGCCGCTCTGTTCACCATCTTCTCGCTGAACGGCGAGCGCTGCACCGCCGGCAGTCGCATCTTCGTCCAGGAAAGCGTCTACCCGCAGTTCGTCGCCGAGTTCGCCGCGCGCGCCAGGCGCCTGATCGTCGGCGATCCGCAGGACCCGAAGACCCAGGTCGGCTCGATGATCACCCAGGCCCACTACGACAAGGTCACCGGCTACATCCGCATCGGCCTCGAGGAAGGCGCCACCCTGGTGGCCGGCGGCCTGGAGCGTCCGGCCGGCCTGCCGGCGCACCTGAGCAAGGGGCAGTTCATCCAGCCCACGGTGTTCGCCGACGTGGACAACCGCATGCGCATCGCCCAGGAGGAGATCTTCGGCCCGGTGGTCTGCCTGATCCCGTTCAAGGACGAAGCCGAGGCGCTGCGCCTGGCCAACGACGTGGAATACGGCCTGGCCTCCTACATCTGGACCCAGGACATCGGCAAGGCCCATCGCCTGGCACGCGGCATCGAGGCCGGGATGGTCTTCATCAACAGCCAGAACGTGCGCGACCTGCGCCAGCCGTTCGGCGGGGTGAAGGCCTCGGGCACCGGACGCGAAGGCGGGGAATACAGCTTCGAGGTATTCGCCGAGATCAAGAACGTGTGTATATCCATGGGCAGCCATCACATCCCCCGCTGGGGCGTGTAG |
Protein Properties |
Protein Residues: |
486 |
Protein Molecular Weight: |
53 kDa |
Protein Theoretical pI: |
6.38 |
Hydropathicity (GRAVY score): |
-0.098 |
Charge at pH 7 (predicted): |
-4.28 |
Protein Sequence: |
>PA4123
MIKHWINGREVESKDVFENYNPATGELIGEVASGGAAEIDAAVAAAREAFPKWANTPAKERARLMRRLGELIDRNVPHLAELETLDTGLPIHQTKNVLIPRASHNFEFFAEVCTRMNGHSYPVDDQMLNYTLYQPVGVCGLVSPWNVPFMTATWKTAPCLALGNTAVLKMSELSPLTANELGRLVHEAGIPPGVFNVVQGYGASAGDALVRHRDVRAVSFTGGTATGRRIMEAAGIKKYSMELGGKSPVLVFEDADLERALDAALFTIFSLNGERCTAGSRIFVQESVYPQFVAEFAARARRLIVGDPQDPKTQVGSMITQAHYDKVTGYIRIGLEEGATLVAGGLERPAGLPAHLSKGQFIQPTVFADVDNRMRIAQEEIFGPVVCLIPFKDEAEALRLANDVEYGLASYIWTQDIGKAHRLARGIEAGMVFINSQNVRDLRQPFGGVKASGTGREGGEYSFEVFAEIKNVCISMGSHHIPRWGV |
References |
External Links: |
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General Reference: |
PaperBLAST - Find papers about PA4123 and its homologs
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