Identification |
Name: |
4-hydroxyphenylacetate 3-monooxygenase large chain p-hydroxyphenylacetate 3-hydroxylase |
Synonyms: |
Not Available |
Gene Name: |
hpaA |
Enzyme Class: |
Not Available |
Biological Properties |
General Function: |
carbon utilization, 4-hydroxyphenylacetate metabolic process, cellular catabolic process, metabolic process, oxidation-reduction process, phenylacetate catabolic process |
Specific Function: |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, flavin adenine dinucleotide binding, acyl-CoA dehydrogenase activity, oxidoreductase activity, acting on the CH-CH group of donors |
Cellular Location: |
Cytoplasmic |
KEGG Pathways: |
|
KEGG Reactions: |
Not Available |
SMPDB Reactions: |
Not Available |
PseudoCyc/BioCyc Reactions: |
| 4-hydroxyphenylacetate + NADH + oxygen = 3,4-dihydroxyphenylacetate + NAD + + H 2O ReactionCard |
|
Complex Reactions: |
Not Available |
Transports: |
Not Available |
Metabolites: |
Not Available |
GO Classification: |
Function |
---|
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | flavin adenine dinucleotide binding | acyl-CoA dehydrogenase activity | oxidoreductase activity, acting on the CH-CH group of donors | Process |
---|
carbon utilization | 4-hydroxyphenylacetate metabolic process | cellular catabolic process | metabolic process | oxidation-reduction process | phenylacetate catabolic process |
|
Gene Properties |
Locus tag: |
PA4091 |
Strand: |
+ |
Entrez Gene ID: |
878727 |
Accession: |
NP_252780.1 |
GI: |
15599286 |
Sequence start: |
4573741 |
Sequence End: |
4575303 |
Sequence Length: |
1562 |
Gene Sequence: |
>PA4091
ATGAAACCCGAAGATTTCCGTGCCTCTGCCACCCGTCCGTTCACCGGCGAGGAGTACCTCGCCAGCCTGCGCGACGACCGTGAGATCTACATCTACGGCGACCGCGTCAAGGACGTCACCAGCCACCCCGCCTTCCGCAACGCGGCCGCCTCCATGGCCCGGCTCTACGACGCCCTGCACGATCCGCAGAGCAAGGAAAAGCTCTGCTGGGAGACCGATACCGGCAACGGCGGCTATACCCACAAGTTCTTCCGCTACGCGCGCAGCGCCGACGAACTGCGCCAGCAGCGCGACGCCATCGCCGAGTGGTCGCGGCTGACCTACGGCTGGATGGGCCGCACCCCGGACTACAAGGCCGCCTTCGGCAGCGCCCTCGGCGCCAACCCGGGCTTCTACGGGCGTTTCGAGGACAACGCGAAAACCTGGTACAAGCGCATCCAGGAAGCCTGCCTGTACCTCAACCATGCCATCGTCAACCCGCCGATCGACCGCGACAAGCCGGTGGACCAGGTCAAGGACGTGTTCATCTCGGTGGACGAGGAAGTCGACGGCGGCATCGTCGTCAGCGGCGCCAAGGTGGTCGCCACGAATTCCGCGCTGACCCACTACAACTTCGTCGGCCAGGGTTCGGCGCAACTGCTCGGCGACAACACCGACTTCGCCCTGATGTTCATCGCGCCGATGAACACCCCCGGCATGAAGCTGATCTGCCGCCCCTCCTACGAACTGGTGGCGGGTATCGCCGGATCGCCGTTCGACTACCCGCTGTCCAGCCGTTTCGACGAGAACGACGCGATCCTGGTGATGGACAAGGTGTTCATCCCCTGGGAGAACGTACTGATCTACCGCGACTTCGAGCGCTGCAAGCAGTGGTTCCCCCAGGGTGGCTTCGGCCGGCTGTTCCCGATGCAGGGCTGCACCCGCCTGGCGGTCAAGCTCGACTTCATCACCGGCGCCCTCTACAAGGCCCTGCAATGCACCGGCTCCCTGGAGTTCCGCGGCGTGCAGGCGCAGGTCGGCGAAGTGGTGGCCTGGCGCAACCTGTTCTGGTCGCTGACCGACGCCATGTACGGCAACGCCAGCGAATGGCACGGCGGCGCCTTCCTGCCCAGCGCCGAGGCCCTGCAGGCCTACCGCGTGCTGGCGCCGCAGGCCTACCCGGAGATCAAGAAGACCATCGAGCAGGTGGTCGCCAGCGGCCTGATCTACCTGCCCTCCGGCGTTCGCGACCTGCACAATCCGCAACTCGACAAGTATCTCTCCACCTATTGCCGCGGCTCCGGCGGCATGGGCCACCGGGAGCGGATCAAGATCCTCAAGCTGCTCTGGGACGCCATCGGCAGCGAGTTCGGCGGCCGCCACGAGCTGTACGAGATCAACTACGCCGGCAGCCAGGACGAGATCCGCATGCAGGCCCTGCGCCAGGCGATCGGCAGCGGGGCGATGAAGGGCATGCTCGGCATGGTCGAGCAGTGCATGGGCGACTACGACGAGAACGGCTGGACCGTGCCGCACCTGCACAACCCGGACGACATCAACGTGCTCGATCGCATCCGCCAATGA |
Protein Properties |
Protein Residues: |
520 |
Protein Molecular Weight: |
58.5 kDa |
Protein Theoretical pI: |
6 |
Hydropathicity (GRAVY score): |
-0.338 |
Charge at pH 7 (predicted): |
-6.58 |
Protein Sequence: |
>PA4091
MKPEDFRASATRPFTGEEYLASLRDDREIYIYGDRVKDVTSHPAFRNAAASMARLYDALHDPQSKEKLCWETDTGNGGYTHKFFRYARSADELRQQRDAIAEWSRLTYGWMGRTPDYKAAFGSALGANPGFYGRFEDNAKTWYKRIQEACLYLNHAIVNPPIDRDKPVDQVKDVFISVDEEVDGGIVVSGAKVVATNSALTHYNFVGQGSAQLLGDNTDFALMFIAPMNTPGMKLICRPSYELVAGIAGSPFDYPLSSRFDENDAILVMDKVFIPWENVLIYRDFERCKQWFPQGGFGRLFPMQGCTRLAVKLDFITGALYKALQCTGSLEFRGVQAQVGEVVAWRNLFWSLTDAMYGNASEWHGGAFLPSAEALQAYRVLAPQAYPEIKKTIEQVVASGLIYLPSGVRDLHNPQLDKYLSTYCRGSGGMGHRERIKILKLLWDAIGSEFGGRHELYEINYAGSQDEIRMQALRQAIGSGAMKGMLGMVEQCMGDYDENGWTVPHLHNPDDINVLDRIRQ |
References |
External Links: |
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General Reference: |
PaperBLAST - Find papers about PA4091 and its homologs
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