Identification
Name: Nitrate/nitrite sensor protein narX
Synonyms: Not Available
Gene Name: narX
Enzyme Class:
Biological Properties
General Function: Signal transduction mechanisms
Specific Function: Acts as a sensor for nitrate/nitrite and transduces signal of nitrate availability to the narL protein and of both nitrate/nitrite to the narP protein. NarX probably activates narL and narP by phosphorylation in the presence of nitrate. NarX also plays a negative role in controlling narL activity, probably through dephosphorylation in the absence of nitrate
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+protein L-histidineThumb+protein N-phospho-L-histidine
Adenosine triphosphate + protein L-histidine → ADP + protein N-phospho-L-histidine
ReactionCard
Complex Reactions:
Thumb+protein L-histidineThumb+protein N-phospho-L-histidine
Adenosine triphosphate + protein L-histidine → ADP + protein N-phospho-L-histidine
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
GO Classification:
Component
cell part
integral to membrane
intrinsic to membrane
membrane
membrane part
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
ATP binding
binding
catalytic activity
kinase activity
molecular transducer activity
nucleoside binding
protein binding
protein dimerization activity
protein histidine kinase activity
protein kinase activity
purine nucleoside binding
signal transducer activity
transferase activity
transferase activity, transferring phosphorus-containing groups
two-component sensor activity
Process
biological regulation
cellular metabolic process
metabolic process
peptidyl-histidine phosphorylation
phosphate metabolic process
phosphorus metabolic process
phosphorylation
protein amino acid phosphorylation
regulation of biological process
regulation of cellular process
signal transduction
signal transmission
signaling process
two-component signal transduction system (phosphorelay)
Gene Properties
Locus tag: PA3878
Strand: +
Entrez Gene ID: 878321
Accession: NP_252567.1
GI: 15599073
Sequence start: 4345010
Sequence End: 4346878
Sequence Length: 1868
Gene Sequence:
>PA3878
ATGAACAAGGCGACCGCGCCGGACGCTGACCAGCGGGACAGATTCTTTGGAGGTAGTGACAGGGCCGGAAAGCCGATCCTGCGCCGCTCCCTGGTAGTCCGCTTCGGCTGCTACCTCACCCTGCTGGTATCGCTGGCGCTGATCGGGATGTTCAGCGCCCTGCTCTTCGCCGACTACACGCACCAGGACGCCGCGGTGATCAACCACGCCGGCTCGTTGCGCATGCTCACCTACCGGGTCGCCCTGGAGCCCAGCCTGGAAGGCCGCCAGGCGCTGCTCGGGACCCTCGGCGAACGCCTCGACAGCGGCGACATCCGCCGCCTGCTGCAACGCCAGGACGCCGACGACCCGATCCGCCAGTTGCACCAGGAGCTGCGCGAGGGCCTCGCGCGCCTGGACCCGCGCGCGCTGCCCGGACGCGCCGTGCTGGACGCCTACGTCGGCGACATCGACCGTTTCGTCGGCATCCTCCAGGCCAAGGCCGAGCGCCGCTCGCAACTGCTCAGCACGGTGCAGGGCCTGTGCCTGTTCCTCAGCCTGCTGGTGGTGTTCGTCACCCTCTACGACCTCAGCTATCACGTCATCGGCCCGCTGCGCGAACTCACCAGCACCGCCCGCCGCCTGGGCCGCGGCGAGCTGGACGCGCGGGTCACCTACAGCGGCGAGGACGAACTGGCGCAACTGGGCGAGCGCTTCAACCAGATGGCCGGCGAGCTGAAGAGCATCTACGGCGACCTGGAAGAGCGCGTGGAGGACAAGACCCGCGCCCTCTCGCAGAGCCACCAGCGCCTCGAACTGCTCTACGCCAGCGCCCGCCGGCTGGGCGAGAACCCCTACGACAGCCGCACCCTGCAACCGCTGCTGAACCAGTTGGAGAAAGTGCTCGACGCCGGCCGCGTGACCCTCTGCCTGAACAAGGACGGGGTCGAGCGCGCCTACAGTTCGCTGACCACCACCGAGCGCCCGGCGGACTTCTGCCTGCAGGGCGACTGCGGTAGCTGCCGCGAGCAGGCCAGCGCCTGCGACCAACCCTCGTCCCTGGCCCAGCCATTGCTGATGCAGCCCCTGTCCATCGCCGGCCACCGTTTCGGCGAACTGTTCATCGAAAGCCGCAGCGGCCGCCTGGAGAACTGGCAGCAGCAACTGATCGAGACCTTCTGCGACAACATCGCCCGCACCTTCGCCCTGTCCCTGCAACAGGAACAGGAAAGCCGCCTGGCCCTGTTCGCCGAGCGCGGCACCATCGCCCGCGAACTGCACGATTCGCTGGCACAGTCGCTGTCCTACCTGAAGATCCAGGTCAGCCGCCTGGGCACCCTGCTCAAGCGCGAGGCGCCGGCGGAGAAGATCGAGGACACCCTCGACGAACTGCGCGAAGGCCTCAACGGCGCCTACCGGCAACTGCGCGAACTGCTCACCACCTTCCGCCTCAGCCTCGACGAGCCGAGCCTGGAAGCCGCGCTGGGGAACGCCGTGGCCGAGTTCGGCGAGCGCGGCGAGGTGACGATCGAACTGGACAACCGCCTGCAACACGTGCCGCTGAGCCCCAACGAGGAAATCCACGTCCTGCAGATCGTCCGCGAGGCGCTCTCCAACGTGGTTCGCCATTCGCAGGCGCAACGGGCCTGGGTGCGCCTGAGCAGCCAGGCCGACGGCCAGGTGAGCATCGCCGTCGAGGACGATGGCGTCGGCTTTGATCCGCAGCAGAACCGCAGCGGCCATTATGGGCTTACCATCATGCAGGAGCGCGGCCAGACCCTCGGCAGCCAGTTGCGCTTCGAAGCGCGCGCGCCCCACGGCACGCGAGTGCTCTTCAGCTTCGTGCCGACCGCCCTGCAACCCTCCGCCGCCAAGGAGCCGACCCCATGA
Protein Properties
Protein Residues: 622
Protein Molecular Weight: 69.3 kDa
Protein Theoretical pI: 5.71
Hydropathicity (GRAVY score): -0.309
Charge at pH 7 (predicted): -9.31
Protein Sequence:
>PA3878
MNKATAPDADQRDRFFGGSDRAGKPILRRSLVVRFGCYLTLLVSLALIGMFSALLFADYTHQDAAVINHAGSLRMLTYRVALEPSLEGRQALLGTLGERLDSGDIRRLLQRQDADDPIRQLHQELREGLARLDPRALPGRAVLDAYVGDIDRFVGILQAKAERRSQLLSTVQGLCLFLSLLVVFVTLYDLSYHVIGPLRELTSTARRLGRGELDARVTYSGEDELAQLGERFNQMAGELKSIYGDLEERVEDKTRALSQSHQRLELLYASARRLGENPYDSRTLQPLLNQLEKVLDAGRVTLCLNKDGVERAYSSLTTTERPADFCLQGDCGSCREQASACDQPSSLAQPLLMQPLSIAGHRFGELFIESRSGRLENWQQQLIETFCDNIARTFALSLQQEQESRLALFAERGTIARELHDSLAQSLSYLKIQVSRLGTLLKREAPAEKIEDTLDELREGLNGAYRQLRELLTTFRLSLDEPSLEAALGNAVAEFGERGEVTIELDNRLQHVPLSPNEEIHVLQIVREALSNVVRHSQAQRAWVRLSSQADGQVSIAVEDDGVGFDPQQNRSGHYGLTIMQERGQTLGSQLRFEARAPHGTRVLFSFVPTALQPSAAKEPTP
References
External Links:
Resource Link
Genome ID: PA3878
Entrez Gene ID: 878321
NCBI Protein ID: 15599073
General Reference: PaperBLAST - Find papers about PA3878 and its homologs