Identification
Name: DNA polymerase III subunit chi
Synonyms: Not Available
Gene Name: holC
Enzyme Class:
Biological Properties
General Function: Involved in DNA binding
Specific Function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Cellular Location: Cytoplasmic
KEGG Pathways:
KEGG Reactions:
Thumb+DNAThumb+DNA
Thumb+DNAThumb+DNA
Thumb+DNAThumb+DNA
Thumb+DNAThumb+DNA
Deoxynucleoside triphosphate+DNAThumb
Deoxynucleoside triphosphate + DNA ↔ Pyrophosphate
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+DNAThumb+DNA
Thumb+DNAThumb+DNA
Thumb+DNAThumb+DNA
Thumb+DNAThumb+DNA
Deoxynucleoside triphosphate+DNA(n)Thumb+DNA(n+1)
Deoxynucleoside triphosphate + DNA(n) → Pyrophosphate + DNA(n+1)
ReactionCard
Deoxynucleoside triphosphate+DNAThumb
Deoxynucleoside triphosphate + DNA ↔ Pyrophosphate
ReactionCard
Complex Reactions:
Deoxynucleoside triphosphate+DNA(n)Thumb+DNA(n+1)
Deoxynucleoside triphosphate + DNA(n) → Pyrophosphate + DNA(n+1)
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000412dATPMetaboCard
PAMDB000219dCTPMetaboCard
PAMDB000389dGTPMetaboCard
PAMDB000633PyrophosphateMetaboCard
PAMDB000346Thymidine 5'-triphosphateMetaboCard
GO Classification:
Function
binding
catalytic activity
DNA binding
DNA polymerase activity
DNA-directed DNA polymerase activity
nucleic acid binding
nucleotidyltransferase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Process
cellular macromolecule metabolic process
DNA metabolic process
DNA replication
macromolecule metabolic process
metabolic process
Gene Properties
Locus tag: PA3832
Strand: +
Entrez Gene ID: 879882
Accession: NP_252521.1
GI: 15599027
Sequence start: 4290427
Sequence End: 4290855
Sequence Length: 428
Gene Sequence:
>PA3832
GTGACCCGGGTCGATTTCTACGTGATCCCCAGCGCCGATCCGTCGGCGCGCCTGCAGGTCGCCTGCCGCCTGGCCGAGAAGGCCTGGCGGCAGGGCATGCAGGTCTACCTGCATTGCGCCGACGAGGCGCAGCGCAGCGAGTTGGACGGCCGCCTGTGGAGCTTCCGCGGCGAGGCCTTCATTCCTCACAGCCTGGCCGAGGAAGACGCCGAGGCGCCCGTCGCCCTGGGCCTGGGCGAGCCCCCGGGGAACCATCGCGACCTGCTGATCAACCTGACCCTCGAGGCCCCCGGCTTCGTCCCGAACTTTTCGCGGGTGGCCGAACTGGTGGTCGAGGAGCCGGCGATCCGCCAGGCGGCACGGGATAAATTCCGCTTCTACCGGGAGCAGGGCTATCCTCTACAGGACCATCGCCTGCCGCGTATCTGA
Protein Properties
Protein Residues: 142
Protein Molecular Weight: 16.1 kDa
Protein Theoretical pI: 5.65
Hydropathicity (GRAVY score): -0.366
Charge at pH 7 (predicted): -3.11
Protein Sequence:
>PA3832
MTRVDFYVIPSADPSARLQVACRLAEKAWRQGMQVYLHCADEAQRSELDGRLWSFRGEAFIPHSLAEEDAEAPVALGLGEPPGNHRDLLINLTLEAPGFVPNFSRVAELVVEEPAIRQAARDKFRFYREQGYPLQDHRLPRI
References
External Links:
Resource Link
Genome ID: PA3832
Entrez Gene ID: 879882
NCBI Protein ID: 15599027
General Reference: PaperBLAST - Find papers about PA3832 and its homologs