Ribosomal RNA large subunit methyltransferase N (PA3806)

Identification
Name: Ribosomal RNA large subunit methyltransferase N
Synonyms:
  • 23S rRNA m2A2503 methyltransferase
Gene Name: rlmN
Enzyme Class:
Biological Properties
General Function: Involved in 4 iron, 4 sulfur cluster binding
Specific Function: Specifically methylates position 2 of adenine 2503 in 23S rRNA
Cellular Location: Cytoplasm (Potential)
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites:
    PAMDB IDNameView
    PAMDB0015835'-DeoxyadenosineMetaboCard
    PAMDB000175L-MethionineMetaboCard
    PAMDB000205S-AdenosylhomocysteineMetaboCard
    GO Classification:
    Component
    cell part
    cytoplasm
    intracellular part
    Function
    binding
    catalytic activity
    iron-sulfur cluster binding
    metal cluster binding
    methyltransferase activity
    RNA methyltransferase activity
    transferase activity
    transferase activity, transferring one-carbon groups
    Process
    cellular macromolecule metabolic process
    macromolecule metabolic process
    metabolic process
    ncRNA metabolic process
    RNA metabolic process
    rRNA metabolic process
    rRNA processing
    Gene Properties
    Locus tag: PA3806
    Strand: -
    Entrez Gene ID: 879171
    Accession: NP_252495.1
    GI: 15599001
    Sequence start: 4265306
    Sequence End: 4266445
    Sequence Length: 1139
    Gene Sequence: 
    >PA3806
ATGACAACGACCACCGCCGGCAAGGTGAACCTGCTGGGCCTGACCCAGCCGCAGCTGGAACAGTTCTTCGAGTCCATCGGCGAGAAGCGTTTCCGGGCCGGCCAGGTCATGAAGTGGATTCACCACTTTGGCGTCGACGATTTCGACGCCATGACCAACGTCGGCAAGGCCTTGCGCGAAAAGCTCAAGGCCTCAGCCGAGATACGCGGTCCCGAGATCGTCAGCCAGGATATTTCCGCCGACGGCACCCGCAAGTGGGTGGTCCGGGTGGCGTCCGGCAGTTGCGTCGAGACCGTGTACATCCCCCAGGGCGGACGCGGCACCCTGTGCGTGTCCTCCCAGGCGGGCTGCGCCCTGGATTGCAGTTTCTGCTCCACCGGCAAGCAGGGTTTCAACAGCGACCTCACCGCCGCCGAGGTGATCGGCCAGGTGTGGATCGCCAACAAGTCGTTCGGTACCGTTCCGGCCAAGATCGACCGCGCCATCACCAATGTCGTGATGATGGGCATGGGCGAGCCGCTGCTGAACTTCGACAACGTGGTCGCCGCCATGAACATCATGATGGACGACCTCGGCTACGGTATTTCCAAGCGCAAGGTGACCCTGTCCACCTCCGGCGTGGTGCCGATGATCGACAAGCTCGGCGAGGTGATCGACGTGTCCCTGGCCCTGTCGCTGCACGCACCGAACGACGAGTTGCGCAACAAGCTGGTGCCGATCAACAAGAAGTATCCGCTGGGCATGCTGCTGGATGCCTGCCGCCGGTATATTTCCCGGCTCGGCGAGAAGCGCGTGCTGACCGTCGAATACACCCTGCTCAAGGATGTCAACGATCAGCCCGAGCATGCTGAGCAGATGATCGCATTGCTGAAAGACACGCCTTGCAAGATCAACCTGATTCCGTTTAATCCATTCCCGCACTCCGGCTACGAGCGCCCGAGCAACAATGCCATCCGGCGTTTCCAGGACATGTTGCACAAGGGCGGCTTCAACGTGACCGTGCGTACCACCCGCGGCGACGACATCGACGCGGCCTGTGGCCAACTGGTTGGTCAGGTCATGGATCGTACCCGCCGGAGCGAACGTTATATTGCCGTGCGCCAACTGGCCGAGTCCGAGTCGGCGGCGAATCGAAATTGA
    Protein Properties
    Protein Residues: 379
    Protein Molecular Weight: 41.7 kDa
    Protein Theoretical pI: 8.39
    Hydropathicity (GRAVY score): -0.188
    Charge at pH 7 (predicted): 5.21
    Protein Sequence: 
    >PA3806
MTTTTAGKVNLLGLTQPQLEQFFESIGEKRFRAGQVMKWIHHFGVDDFDAMTNVGKALREKLKASAEIRGPEIVSQDISADGTRKWVVRVASGSCVETVYIPQGGRGTLCVSSQAGCALDCSFCSTGKQGFNSDLTAAEVIGQVWIANKSFGTVPAKIDRAITNVVMMGMGEPLLNFDNVVAAMNIMMDDLGYGISKRKVTLSTSGVVPMIDKLGEVIDVSLALSLHAPNDELRNKLVPINKKYPLGMLLDACRRYISRLGEKRVLTVEYTLLKDVNDQPEHAEQMIALLKDTPCKINLIPFNPFPHSGYERPSNNAIRRFQDMLHKGGFNVTVRTTRGDDIDAACGQLVGQVMDRTRRSERYIAVRQLAESESAANRN
    References
    External Links:
    Resource Link
    Genome ID: PA3806
    Entrez Gene ID: 879171
    NCBI Protein ID: 15599001
    General Reference: PaperBLAST - Find papers about PA3806 and its homologs