Identification
Name: elastase LasB neutral metalloproteinase; pseudolysin precursor
Synonyms: Not Available
Gene Name: lasB
Enzyme Class: Not Available
Biological Properties
General Function: cellular protein metabolic process, elastin biosynthetic process, elastin catabolic process, elastin catabolic process, proteolysis, bacterial-type flagellum-dependent swarming motility, single-species biofilm formation, bacterial-type flagellum-dependent swarming motility, single-species biofilm formation, protein secretion by the type II secretion system, protein transport by the Sec complex, interaction with host via protein secreted by type II secretion system
Specific Function: metalloendopeptidase activity
Cellular Location: Extracellular
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    a protein + H2O → a peptide + a peptide
    ReactionCard
    a protein + H2O → 2 a peptide
    ReactionCard
    a protein + H2O → a peptide + a peptide
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    metalloendopeptidase activity
    Process
    cellular protein metabolic process
    elastin biosynthetic process
    elastin catabolic process
    elastin catabolic process
    proteolysis
    bacterial-type flagellum-dependent swarming motility
    single-species biofilm formation
    bacterial-type flagellum-dependent swarming motility
    single-species biofilm formation
    protein secretion by the type II secretion system
    protein transport by the Sec complex
    interaction with host via protein secreted by type II secretion system
    Gene Properties
    Locus tag: PA3724
    Strand: -
    Entrez Gene ID: 880368
    Accession: NP_252413.1
    GI: 15598919
    Sequence start: 4168987
    Sequence End: 4170483
    Sequence Length: 1496
    Gene Sequence:
    >PA3724
    ATGAAGAAGGTTTCTACGCTTGACCTGTTGTTCGTTGCGATCATGGGTGTTTCGCCGGCCGCTTTTGCCGCCGACCTGATCGACGTGTCCAAACTCCCCAGCAAGGCTGCCCAGGGCGCGCCCGGCCCGGTCACCTTGCAAGCCGCGGTCGGCGCTGGCGGTGCCGACGAACTGAAAGCGATCCGCAGCACGACCCTGCCCAACGGCAAGCAGGTCACCCGCTACGAGCAATTCCACAACGGCGTACGGGTGGTCGGCGAAGCCATCACCGAAGTCAAGGGTCCCGGCAAGAGCGTGGCGGCGCAGCGCAGCGGCCATTTCGTCGCCAACATCGCTGCCGACCTGCCGGGCAGCACCACCGCGGCGGTATCCGCCGAGCAGGTGCTGGCCCAGGCCAAGAGCCTGAAGGCCCAGGGCCGCAAGACCGAGAATGACAAAGTGGAACTGGTGATCCGCCTGGGCGAGAACAACATCGCCCAACTGGTCTACAACGTCTCCTACCTGATTCCCGGCGAGGGACTGTCGCGGCCGCATTTCGTCATCGACGCCAAGACCGGCGAAGTGCTCGATCAGTGGGAAGGCCTGGCCCACGCCGAGGCGGGCGGCCCCGGCGGCAACCAGAAGATCGGCAAGTACACCTACGGTAGCGACTACGGTCCGCTGATCGTCAACGACCGCTGCGAGATGGACGACGGCAACGTCATCACCGTCGACATGAACAGCAGCACCGACGACAGCAAGACCACGCCGTTCCGCTTCGCCTGCCCGACCAACACCTACAAGCAGGTCAACGGCGCCTATTCGCCGCTGAACGACGCGCATTTCTTCGGCGGCGTGGTGTTCAAACTGTACCGGGACTGGTTCGGCACCAGCCCGCTGACCCACAAGCTGTACATGAAGGTGCACTACGGGCGCAGCGTGGAGAACGCCTACTGGGACGGCACGGCGATGCTCTTCGGCGACGGCGCCACCATGTTCTATCCGCTGGTGTCGCTGGACGTGGCGGCCCACGAGGTCAGCCACGGCTTCACCGAGCAGAACTCCGGGCTGATCTACCGCGGGCAATCAGGCGGAATGAACGAAGCGTTCTCCGACATGGCCGGCGAGGCTGCCGAGTTCTATATGCGCGGCAAGAACGACTTCCTGATCGGCTACGACATCAAGAAGGGCAGCGGTGCGCTGCGCTACATGGACCAGCCCAGCCGCGACGGGCGATCCATCGACAACGCGTCGCAGTACTACAACGGCATCGACGTGCACCACTCCAGCGGCGTGTACAACCGTGCGTTCTACCTGTTGGCCAATTCGCCGGGCTGGGATACCCGCAAGGCCTTCGAGGTGTTCGTCGACGCCAACCGCTACTACTGGACCGCCACCAGCAACTACAACAGCGGCGCCTGCGGGGTGATTCGCTCGGCGCAGAACCGCAACTACTCGGCGGCTGACGTCACCCGGGCGTTCAGCACCGTCGGCGTGACCTGCCCGAGCGCGTTGTAA
    Protein Properties
    Protein Residues: 498
    Protein Molecular Weight: 53.7 kDa
    Protein Theoretical pI: 6.74
    Hydropathicity (GRAVY score): -0.271
    Charge at pH 7 (predicted): -1.48
    Protein Sequence:
    >PA3724
    MKKVSTLDLLFVAIMGVSPAAFAADLIDVSKLPSKAAQGAPGPVTLQAAVGAGGADELKAIRSTTLPNGKQVTRYEQFHNGVRVVGEAITEVKGPGKSVAAQRSGHFVANIAADLPGSTTAAVSAEQVLAQAKSLKAQGRKTENDKVELVIRLGENNIAQLVYNVSYLIPGEGLSRPHFVIDAKTGEVLDQWEGLAHAEAGGPGGNQKIGKYTYGSDYGPLIVNDRCEMDDGNVITVDMNSSTDDSKTTPFRFACPTNTYKQVNGAYSPLNDAHFFGGVVFKLYRDWFGTSPLTHKLYMKVHYGRSVENAYWDGTAMLFGDGATMFYPLVSLDVAAHEVSHGFTEQNSGLIYRGQSGGMNEAFSDMAGEAAEFYMRGKNDFLIGYDIKKGSGALRYMDQPSRDGRSIDNASQYYNGIDVHHSSGVYNRAFYLLANSPGWDTRKAFEVFVDANRYYWTATSNYNSGACGVIRSAQNRNYSAADVTRAFSTVGVTCPSAL
    References
    External Links:
    Resource Link
    Genome ID: PA3724
    Entrez Gene ID: 880368
    NCBI Protein ID: 15598919
    General Reference: PaperBLAST - Find papers about PA3724 and its homologs