Nicotinamide-nucleotide amidohydrolase PncC (PA3618)

Identification
Name: Nicotinamide-nucleotide amidohydrolase PncC
Synonyms: Not Available
Gene Name: pncC
Enzyme Class:
Biological Properties
General Function: pyridine nucleotide biosynthetic process
Specific Function: Has nicotinamidemononucleotide (NMN) aminohydrolase activity, not active on other substrates.
Cellular Location: Not Available
KEGG Pathways:
  • Nicotinate and nicotinamide metabolism pae00760
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb
NMN + Water ↔ Nicotinamide ribotide + Ammonia
ReactionCard
SMPDB Reactions:
beta-nicotinamide D-ribonucleotide+Thumb+Thumb → Thumb+nicotinate beta-D-ribonucleotide+Thumb
beta-nicotinamide D-ribonucleotide + Water + NMN → Ammonium + nicotinate beta-D-ribonucleotide + Nicotinamide ribotide
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb
NMN + Water ↔ Nicotinamide ribotide + Ammonia
ReactionCard
beta-nicotinamide D-ribonucleotide+Thumb+Thumb → Thumb+nicotinate beta-D-ribonucleotide+Thumb
beta-nicotinamide D-ribonucleotide + Water + NMN → Ammonium + nicotinate beta-D-ribonucleotide + Nicotinamide ribotide
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000017AmmoniaMetaboCard
PAMDB001595AmmoniumMetaboCard
PAMDB000095Nicotinamide ribotideMetaboCard
PAMDB003612NMNMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
nicotinamide-nucleotide amidase activity
pyridine nucleotide biosynthetic process
Gene Properties
Locus tag: PA3618
Strand: -
Entrez Gene ID: 880187
Accession: NP_252308.1
GI: 15598814
Sequence start: 4052738
Sequence End: 4053244
Sequence Length: 506
Gene Sequence: 
>PA3618
ATGACCCTGATGGAGTCCGACCTGACCGCACTGGCCGCCCGCCTCGGCGAAAGCCTTCGTTACCTGGGCGAGCAGGTCAGCACGGCGGAATCCTGCACCGGTGGCGGCATCGCCGAGGCGATCACCCGCATCCCGGGGAGTTCGGGCTGGTTCGAGGCTGGCTACGTGACCTACTCGAACCGCCAGAAGACCCTCCAGCTGGAGGTGCCCGAGTCGCTGTTCCCGGCAGTCGGCGCGGTCAGCCGGGAAGTGGTCGAGGCCATGGTGCGCGGCGCCCAGCGGCACAGCGGGGCGCGTTTCGCGGTGGCGGTGAGCGGTGTCGCCGGGCCCGACGGCGGCTCGCCGGAAAAGCCGGTAGGCACGGTCTGGCTGGCCTGGGCCGACGGCGAGCGGCTGGTCAGTGAGCGCTGCCAGTTCAACGGCGACCGCGACGCCGTGCGCCGGCAGACGGTGGCGACCGCGCTGACCGGCCTGCTGCGCATGAGCAACGGCGAGAACCCGGGCTAG
Protein Properties
Protein Residues: 168
Protein Molecular Weight: 17.7 kDa
Protein Theoretical pI: 4.99
Hydropathicity (GRAVY score): -0.16
Charge at pH 7 (predicted): -2.83
Protein Sequence: 
>PA3618
MTLMESDLTALAARLGESLRYLGEQVSTAESCTGGGIAEAITRIPGSSGWFEAGYVTYSNRQKTLQLEVPESLFPAVGAVSREVVEAMVRGAQRHSGARFAVAVSGVAGPDGGSPEKPVGTVWLAWADGERLVSERCQFNGDRDAVRRQTVATALTGLLRMSNGENPG
References
External Links:
Resource Link
Genome ID: PA3618
Entrez Gene ID: 880187
NCBI Protein ID: 15598814
General Reference: PaperBLAST - Find papers about PA3618 and its homologs