Identification |
Name: |
3-hydroxyisobutyrate dehydrogenase |
Synonyms: |
Not Available |
Gene Name: |
mmsB |
Enzyme Class: |
Not Available |
Biological Properties |
General Function: |
isoleucine catabolic process, leucine catabolic process, carbon utilization, cellular catabolic process, pentose-phosphate shunt, oxidation-reduction process, valine metabolic process |
Specific Function: |
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity, phosphogluconate dehydrogenase (decarboxylating) activity, 3-hydroxyisobutyrate dehydrogenase activity, NAD binding, oxidoreductase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, coenzyme binding |
Cellular Location: |
Cytoplasmic |
KEGG Pathways: |
|
KEGG Reactions: |
Not Available |
SMPDB Reactions: |
Not Available |
PseudoCyc/BioCyc Reactions: |
| ( S)-3-hydroxy-isobutanoate + NAD + → ( S)-methylmalonate-semialdehyde + NADH + H +ReactionCard |
|
Complex Reactions: |
Not Available |
Transports: |
Not Available |
Metabolites: |
Not Available |
GO Classification: |
Function |
---|
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity | phosphogluconate dehydrogenase (decarboxylating) activity | 3-hydroxyisobutyrate dehydrogenase activity | NAD binding | oxidoreductase activity | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | coenzyme binding | Process |
---|
isoleucine catabolic process | leucine catabolic process | carbon utilization | cellular catabolic process | pentose-phosphate shunt | oxidation-reduction process | valine metabolic process |
|
Gene Properties |
Locus tag: |
PA3569 |
Strand: |
- |
Entrez Gene ID: |
879097 |
Accession: |
NP_252259.1 |
GI: |
15598765 |
Sequence start: |
4001196 |
Sequence End: |
4002092 |
Sequence Length: |
896 |
Gene Sequence: |
>PA3569
ATGACCGACATCGCATTCCTCGGCCTGGGCAACATGGGTGGGCCGATGGCCGCCAACCTGCTCAAGGCCGGCCACCGGGTGAATGTCTTCGACTTGCAGCCCAAGGCCGTGCTGGGCCTGGTCGAGCAGGGCGCGCAGGGCGCCGATAGCGCCTTGCAGTGCTGCGAAGGCGCCGAAGTGGTGATCAGCATGCTGCCGGCCGGGCAGCACGTGGAAAGCCTGTATCTCGGCGACGACGGCCTGCTCGCGCGGGTCGCCGGCAAGCCCCTGCTGATCGACTGCTCGACCATCGCCCCGGAGACCGCGCGCAAGGTCGCCGAGGCCGCCGCGGCGAAGGGCCTGACCCTGCTCGACGCGCCGGTTTCCGGCGGCGTCGGCGGCGCCCGCGCCGGCACCCTGAGCTTCATCGTCGGCGGCCCCGCCGAAGGCTTCGCGCGGGCCCGGCCGGTCCTCGAGAACATGGGCCGGAACATCTTCCACGCCGGCGATCACGGCGCCGGCCAGGTGGCGAAGATCTGCAACAACATGCTCCTCGGCATCCTCATGGCCGGCACCGCCGAGGCCCTGGCGCTGGGGGTGAAGAACGGCCTCGACCCGGCGGTGCTGTCCGAGGTGATGAAGCAGAGTTCCGGCGGCAACTGGGCGCTGAACCTCTACAACCCCTGGCCCGGGGTGATGCCGCAGGCGCCGGCGAGCAACGGCTATGCCGGCGGTTTCCAGGTGCGCCTGATGAACAAGGACCTCGGCCTGGCGCTGGCCAACGCCCAGGCGGTGCAGGCCTCGACGCCGCTCGGCGCGCTGGCGCGCAACCTGTTCAGCCTGCACGCCCAGGCCGATGCCGAGCACGAGGGGCTGGACTTCTCCAGCATCCAGAAGCTCTACCGCGGCAAGGACTGA |
Protein Properties |
Protein Residues: |
298 |
Protein Molecular Weight: |
30.5 kDa |
Protein Theoretical pI: |
6.24 |
Hydropathicity (GRAVY score): |
0.183 |
Charge at pH 7 (predicted): |
-2.68 |
Protein Sequence: |
>PA3569
MTDIAFLGLGNMGGPMAANLLKAGHRVNVFDLQPKAVLGLVEQGAQGADSALQCCEGAEVVISMLPAGQHVESLYLGDDGLLARVAGKPLLIDCSTIAPETARKVAEAAAAKGLTLLDAPVSGGVGGARAGTLSFIVGGPAEGFARARPVLENMGRNIFHAGDHGAGQVAKICNNMLLGILMAGTAEALALGVKNGLDPAVLSEVMKQSSGGNWALNLYNPWPGVMPQAPASNGYAGGFQVRLMNKDLGLALANAQAVQASTPLGALARNLFSLHAQADAEHEGLDFSSIQKLYRGKD |
References |
External Links: |
|
General Reference: |
PaperBLAST - Find papers about PA3569 and its homologs
|