Identification
Name: 3-hydroxyisobutyrate dehydrogenase
Synonyms: Not Available
Gene Name: mmsB
Enzyme Class: Not Available
Biological Properties
General Function: isoleucine catabolic process, leucine catabolic process, carbon utilization, cellular catabolic process, pentose-phosphate shunt, oxidation-reduction process, valine metabolic process
Specific Function: glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity, phosphogluconate dehydrogenase (decarboxylating) activity, 3-hydroxyisobutyrate dehydrogenase activity, NAD binding, oxidoreductase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, coenzyme binding
Cellular Location: Cytoplasmic
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb
(S)-3-hydroxy-isobutanoate + NAD+ → (S)-methylmalonate-semialdehyde + NADH + H+
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites: Not Available
GO Classification:
Function
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
phosphogluconate dehydrogenase (decarboxylating) activity
3-hydroxyisobutyrate dehydrogenase activity
NAD binding
oxidoreductase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
coenzyme binding
Process
isoleucine catabolic process
leucine catabolic process
carbon utilization
cellular catabolic process
pentose-phosphate shunt
oxidation-reduction process
valine metabolic process
Gene Properties
Locus tag: PA3569
Strand: -
Entrez Gene ID: 879097
Accession: NP_252259.1
GI: 15598765
Sequence start: 4001196
Sequence End: 4002092
Sequence Length: 896
Gene Sequence:
>PA3569
ATGACCGACATCGCATTCCTCGGCCTGGGCAACATGGGTGGGCCGATGGCCGCCAACCTGCTCAAGGCCGGCCACCGGGTGAATGTCTTCGACTTGCAGCCCAAGGCCGTGCTGGGCCTGGTCGAGCAGGGCGCGCAGGGCGCCGATAGCGCCTTGCAGTGCTGCGAAGGCGCCGAAGTGGTGATCAGCATGCTGCCGGCCGGGCAGCACGTGGAAAGCCTGTATCTCGGCGACGACGGCCTGCTCGCGCGGGTCGCCGGCAAGCCCCTGCTGATCGACTGCTCGACCATCGCCCCGGAGACCGCGCGCAAGGTCGCCGAGGCCGCCGCGGCGAAGGGCCTGACCCTGCTCGACGCGCCGGTTTCCGGCGGCGTCGGCGGCGCCCGCGCCGGCACCCTGAGCTTCATCGTCGGCGGCCCCGCCGAAGGCTTCGCGCGGGCCCGGCCGGTCCTCGAGAACATGGGCCGGAACATCTTCCACGCCGGCGATCACGGCGCCGGCCAGGTGGCGAAGATCTGCAACAACATGCTCCTCGGCATCCTCATGGCCGGCACCGCCGAGGCCCTGGCGCTGGGGGTGAAGAACGGCCTCGACCCGGCGGTGCTGTCCGAGGTGATGAAGCAGAGTTCCGGCGGCAACTGGGCGCTGAACCTCTACAACCCCTGGCCCGGGGTGATGCCGCAGGCGCCGGCGAGCAACGGCTATGCCGGCGGTTTCCAGGTGCGCCTGATGAACAAGGACCTCGGCCTGGCGCTGGCCAACGCCCAGGCGGTGCAGGCCTCGACGCCGCTCGGCGCGCTGGCGCGCAACCTGTTCAGCCTGCACGCCCAGGCCGATGCCGAGCACGAGGGGCTGGACTTCTCCAGCATCCAGAAGCTCTACCGCGGCAAGGACTGA
Protein Properties
Protein Residues: 298
Protein Molecular Weight: 30.5 kDa
Protein Theoretical pI: 6.24
Hydropathicity (GRAVY score): 0.183
Charge at pH 7 (predicted): -2.68
Protein Sequence:
>PA3569
MTDIAFLGLGNMGGPMAANLLKAGHRVNVFDLQPKAVLGLVEQGAQGADSALQCCEGAEVVISMLPAGQHVESLYLGDDGLLARVAGKPLLIDCSTIAPETARKVAEAAAAKGLTLLDAPVSGGVGGARAGTLSFIVGGPAEGFARARPVLENMGRNIFHAGDHGAGQVAKICNNMLLGILMAGTAEALALGVKNGLDPAVLSEVMKQSSGGNWALNLYNPWPGVMPQAPASNGYAGGFQVRLMNKDLGLALANAQAVQASTPLGALARNLFSLHAQADAEHEGLDFSSIQKLYRGKD
References
External Links:
Resource Link
Genome ID: PA3569
Entrez Gene ID: 879097
NCBI Protein ID: 15598765
General Reference: PaperBLAST - Find papers about PA3569 and its homologs