ADP-L-glycero-D-manno-heptose-6-epimerase (PA3337)

Identification
Name: ADP-L-glycero-D-manno-heptose-6-epimerase
Synonyms:
  • ADP-L-glycero-beta-D-manno-heptose-6-epimerase
  • ADP-glyceromanno-heptose 6-epimerase
  • ADP-hep 6-epimerase
  • AGME
Gene Name: hldD
Enzyme Class:
Biological Properties
General Function: Involved in catalytic activity
Specific Function: Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb ↔ Thumb
ADP-D-Glycero-D-manno-heptose ↔ ADP-L-Glycero-D-manno-heptose
ReactionCard
SMPDB Reactions:
Thumb → Thumb
ADP-D-Glycero-D-manno-heptose → ADP-L-glycero-beta-D-manno-heptose
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb ↔ Thumb
ADP-D-Glycero-D-manno-heptose ↔ ADP-L-Glycero-D-manno-heptose
ReactionCard
Complex Reactions:
Thumb → Thumb
ADP-D-Glycero-D-manno-heptose → ADP-L-Glycero-D-manno-heptose
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000960ADP-D-Glycero-D-manno-heptoseMetaboCard
PAMDB006297ADP-L-glycero-beta-D-manno-heptoseMetaboCard
PAMDB000961ADP-L-Glycero-D-manno-heptoseMetaboCard
GO Classification:
Function
ADP-glyceromanno-heptose 6-epimerase activity
binding
catalytic activity
coenzyme binding
cofactor binding
isomerase activity
NADP or NADPH binding
nucleotide binding
racemase and epimerase activity
racemase and epimerase activity, acting on carbohydrates and derivatives
Process
carbohydrate metabolic process
cellular metabolic process
metabolic process
primary metabolic process
Gene Properties
Locus tag: PA3337
Strand: -
Entrez Gene ID: 882502
Accession: NP_252027.1
GI: 15598533
Sequence start: 3746078
Sequence End: 3747076
Sequence Length: 998
Gene Sequence: 
>PA3337
GTGCCCATGAGCATCATCGTCACCGGCGCCGCCGGCTTCATCGGCAGCAATCTGCTGCAGGCGCTGAACCGGCGCGGCGAGACCGACATCATCGCGGTGGACGATCTCACCGACGGCGAGCAGTTCCGCAACCTGGCGGACGCCGATATCGCCGACTACCTGGACCAGAACGACTTCCTCGAGCGTTACGCCCGCGGCGACTTCGGCACGGTCCGCGCGCTGTTCCACCAGGGCGCCTGCGCCAGCACCCTGGAAAGCAATGGCCGCTACATGATGGAGAACAACTACCGCTACAGTTGCCGCCTGCTGGAAAGCAGCCTGGAACTCGGCGTGCCGTTCCTCTACGCCTCGTCGGCGGCGGTCTACGGCTCCGGCCGGACCTTCCGCGAGGCGCGCCAGTACGAGCGGCCGCTGAACGTCTACGGCTATTCCAAGTTCCTCTTCGACCAGCGTGTGCGGCGGGCGCTGCCGCAGGCGCGCAGCCAGGTGGTCGGCCTGCGTTACTTCAACGTCTACGGGCCGCGCGAGGAACACAAGGGGCGGATGGCCTCGGTGGCCTACCACTGCTACCAGCAATTGCGCCGCGACGGGCGGGTCGAACTGTTCGGCGAACACGGCGGCTTCCCGCCCGGCGGCCACCTGCGCGACTTCGTCGCGGTGGAGGACGTGGCGCGGGTAAACCTGCATTTCTTCGACCATCCGCAGCGTTCGGGAATCTTCAACCTCGGCAGCGGCCAGGCACGGACCTTCAACGAGGTCGCCCTGGCGGTGATCAATAGCGTCCGCGCCAACGCCGACCAGCCGCCCCTGTCGCTGCAACAGGCCGTGGAAAGCGGCCTGCTCGGCTACCGCGAGTTCCCCGAGTCGCTGCGGGCGCGCTACCAGAGCCATACCTGCGCCGACCTGGAGCTGCTGCGCGAGGCGGGCTACCGCGACGATTTCCAGAGCCTGGAAGAGGGCGTCGCCGGCTACTGCCGCTGGCTGGCGCGCAGCGCCTGA
Protein Properties
Protein Residues: 332
Protein Molecular Weight: 37.4 kDa
Protein Theoretical pI: 6.51
Hydropathicity (GRAVY score): -0.391
Charge at pH 7 (predicted): -2.23
Protein Sequence: 
>PA3337
MPMSIIVTGAAGFIGSNLLQALNRRGETDIIAVDDLTDGEQFRNLADADIADYLDQNDFLERYARGDFGTVRALFHQGACASTLESNGRYMMENNYRYSCRLLESSLELGVPFLYASSAAVYGSGRTFREARQYERPLNVYGYSKFLFDQRVRRALPQARSQVVGLRYFNVYGPREEHKGRMASVAYHCYQQLRRDGRVELFGEHGGFPPGGHLRDFVAVEDVARVNLHFFDHPQRSGIFNLGSGQARTFNEVALAVINSVRANADQPPLSLQQAVESGLLGYREFPESLRARYQSHTCADLELLREAGYRDDFQSLEEGVAGYCRWLARSA
References
External Links:
Resource Link
Genome ID: PA3337
Entrez Gene ID: 882502
NCBI Protein ID: 15598533
General Reference: PaperBLAST - Find papers about PA3337 and its homologs