DNA topoisomerase I (PA3011)

Identification
Name: DNA topoisomerase I
Synonyms: Not Available
Gene Name: topA
Enzyme Class: Not Available
Biological Properties
General Function: DNA metabolic process, DNA topological change
Specific Function: DNA binding, DNA topoisomerase type I activity, DNA topoisomerase activity, DNA topoisomerase type II (ATP-hydrolyzing) activity
Cellular Location: Cytoplasmic
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    a negatively supercoiled DNA = a relaxed DNA
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Component
    chromosome
    Function
    DNA binding
    DNA topoisomerase type I activity
    DNA topoisomerase activity
    DNA topoisomerase type II (ATP-hydrolyzing) activity
    Process
    DNA metabolic process
    DNA topological change
    Gene Properties
    Locus tag: PA3011
    Strand: -
    Entrez Gene ID: 880353
    Accession: NP_251701.1
    GI: 15598207
    Sequence start: 3370100
    Sequence End: 3372706
    Sequence Length: 2606
    Gene Sequence: 
    >PA3011
ATGGGTAAATCGCTGGTCATCGTGGAATCCCCGGCCAAGGCCAAGACCATCAACAAGTACCTGGGCAGCCAGTACGTGGTGAAGTCGAGCATCGGCCACATCCGTGACCTGCCCACCAGTGGTTCGTCGAGTTCCAAGGAGCCGGCGGCCAAGGGCCGCAAGAGCGCCTCCGAGGCGCCGGCGCTGTCACCGAAGGAGAAGGCCAGGCGCCAACTGGTCTCGCGCATGGGGGTCGACCCCGAGCATGGCTGGAAGGCCAAGTACGAGATCCTGCCCGGCAAGGAAAAGGTCATCGACGAGCTGCGCCGCCTGGCCAAGGACGCCGACACCGTCTATCTCGCGACCGACTTGGACCGCGAAGGGGAGGCCATCGCCTGGCACCTGCGGGAAGCCATCGGCGGCGACGAAAGCCGCTACAAGCGCGTGGTATTCAACGAAATCACCAAGAAGGCCATCCAGGAGGCCTTCTCCCAGCCCGGCGAGCTCGATATCAACCGGGTGAACGCCCAGCAGGCGCGGCGTTTCCTCGACCGCGTGGTCGGCTACATGGTCTCGCCGCTGCTCTGGCAGAAGATTGCCCGTGGGTTGTCCGCCGGCCGCGTGCAGTCGGTGGCGGTGAAGCTGGTGGTGGAGCGCGAACGCGAGATTCGCGCCTTCGTCCCGGAAGAGTACTGGGAAGTGCATGCCGACCTCGGTACCGCCAAGGGCGCCAACGTGCGCTTCGAGGTTACCCGTGAGAAGGGCGAGGCCTTCAAGCCGCTCAACGAAGCCCAGGCCATGGCGGCCCTGGAAAAGCTCAAGGCCTCGGCCTATAGCGTCGCCAAGCGCGAGGACCGGCCGACCTCCAGCCGACCCTCGGCGCCGTTCATCACTTCCACCCTGCAGCAGGCGGCGAGCAACCGCCTGGGCTTCGGGGTGAAGAAGACCATGATGATGGCCCAGCGTCTCTACGAGGCCGGCTACATCACCTACATGCGTACCGACTCGACCAACCTGTCGGCCGATGCCATTGGCATGGTCCGCGGTTTCATCGAGGACGAGTTCGGCCAGAAGTACCTGCCGGGCAAGGCCAACGTCTACTCGAGCAAGGAGGGCGCCCAGGAAGCGCACGAGGCGATCCGTCCTTCCGACGTCAACCTCAAGCCGACCCAGCTGTCCGGCATGGAGCGTGACGCCGAGCGCCTGTACGACCTGATCTGGCGCCAGTTCGTGGCGTGCCAGATGACCCCGGCCGAATACCTCTCGACCAGCGTGAGCGTCACCGCCGGCGATTTCGAGCTGCGCGCCAAGGGCCGCATCCTCAAGTTCGACGGTTATACCCGGGTACTGCCGCAGCAGAGCAAGCCGGGCGAGGACGACGTCCTGCCGGAAATGAAGGAAGGCGAGAACCTCAAGCTGATCAAGCTCGATCCGAGCCAGCACTTCACCAAGCCGCCGGCGCGCTACTCCGAAGCGAGCCTGGTCAAGGAACTGGAGAAGCGCGGTATCGGCCGCCCCTCGACCTACGCGGCGATCATCTCCACCATCCAGGAGCGCGGCTACGTAACCACCCACAACCGCCGCTTCTATGCGGAGAAGATGGGCGACATCGTCACCGATCGGCTCAACGAGAGCTTCGCCAACCTGATGGACTACGGTTTCACCGCCGGGATGGAGGAGCATCTCGACGACGTGGCCCAGGGCGAGCGCGACTGGAAGCACCTGCTCGACGAGTTCTACGGCGATTTCAAGAAGAAGCTCGAGGTGGCCGAAGTCAGCGAGAAGGGGATGCGCGCCAACCAGCCGACCCTGACCAACATTCCCTGCCGCGAGTGCGGCCGGCCGATGATGATTCGTACCGCCTCCACCGGCGTGTTCCTCGGCTGCTCGGGCTACAGCCTGCCGCCGAAGGAGCGTTGCAAGGCGACCGTCAACCTGATTCCCGGCGACGAGATCGCCGCGGACGACGAGGGCGAGTCCGAGTCGCGGGTGTTGCGTGGCAAGCATCGCTGCCCGATCTGCAGTACCGCGATGGACGCCTACCTGCTGGACGAGAAACACAAGCTGCATATCTGCGGCAACAACCCCGACTGTCCGGGCTACGAGATCGAGGAAGGCCAGTACCGGATCAAGGGCTACGAAGGGCCGAGCCTGGAATGCGACAAGTGTGGCAGCGAGATGCAGTTGAAGACCGGCCGTTTCGGCAAGTTCTTCGGTTGCACCAATCCGACCTGCAAGAACACCCGCAAGCTGCTGAAGAATGGCGAGGCGGCGCCGCCGAAGATGGACGCCATCCGCATGCCTGAATTGAAGTGCGAGAAGGTGGACGATATCTACGTGCTGCGCGACGGCGCTTCGGGCATGTTCCTGGCCGCCAGCCAGTTCCCGAAGAACCGCGAGACCCGCGCGCCGTTGGTGAGCGAGATCATCCCGCACAAGGCCGAGCTGGATCCCAAGTACCATTACCTCTGCGACGCCCCGCAGAAAGACCCGGACGGCCGTCCCGCGGTGATCCGTTTCAGCCGCAAGACCAAGGAGCAATACGTGCAGTCCGAGGTCGATGGCAAGCCCACCGGCTGGCGCGCCTTCTACGATGGCGGCAAGTGGAAGGTCGAAGACAAGCGCTGA
    Protein Properties
    Protein Residues: 868
    Protein Molecular Weight: 97.3 kDa
    Protein Theoretical pI: 8.66
    Hydropathicity (GRAVY score): -0.617
    Charge at pH 7 (predicted): 13.98
    Protein Sequence: 
    >PA3011
MGKSLVIVESPAKAKTINKYLGSQYVVKSSIGHIRDLPTSGSSSSKEPAAKGRKSASEAPALSPKEKARRQLVSRMGVDPEHGWKAKYEILPGKEKVIDELRRLAKDADTVYLATDLDREGEAIAWHLREAIGGDESRYKRVVFNEITKKAIQEAFSQPGELDINRVNAQQARRFLDRVVGYMVSPLLWQKIARGLSAGRVQSVAVKLVVEREREIRAFVPEEYWEVHADLGTAKGANVRFEVTREKGEAFKPLNEAQAMAALEKLKASAYSVAKREDRPTSSRPSAPFITSTLQQAASNRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSADAIGMVRGFIEDEFGQKYLPGKANVYSSKEGAQEAHEAIRPSDVNLKPTQLSGMERDAERLYDLIWRQFVACQMTPAEYLSTSVSVTAGDFELRAKGRILKFDGYTRVLPQQSKPGEDDVLPEMKEGENLKLIKLDPSQHFTKPPARYSEASLVKELEKRGIGRPSTYAAIISTIQERGYVTTHNRRFYAEKMGDIVTDRLNESFANLMDYGFTAGMEEHLDDVAQGERDWKHLLDEFYGDFKKKLEVAEVSEKGMRANQPTLTNIPCRECGRPMMIRTASTGVFLGCSGYSLPPKERCKATVNLIPGDEIAADDEGESESRVLRGKHRCPICSTAMDAYLLDEKHKLHICGNNPDCPGYEIEEGQYRIKGYEGPSLECDKCGSEMQLKTGRFGKFFGCTNPTCKNTRKLLKNGEAAPPKMDAIRMPELKCEKVDDIYVLRDGASGMFLAASQFPKNRETRAPLVSEIIPHKAELDPKYHYLCDAPQKDPDGRPAVIRFSRKTKEQYVQSEVDGKPTGWRAFYDGGKWKVEDKR
    References
    External Links:
    Resource Link
    Genome ID: PA3011
    Entrez Gene ID: 880353
    NCBI Protein ID: 15598207
    General Reference: PaperBLAST - Find papers about PA3011 and its homologs