precorrin-3 methylase (PA2948)

Identification
Name: precorrin-3 methylase
Synonyms: cbiF
Gene Name: cobM
Enzyme Class: Not Available
Biological Properties
General Function: cofactor biosynthetic process, oxidation-reduction process, metabolic process, cobalamin biosynthetic process, porphyrin-containing compound biosynthetic process
Specific Function: precorrin-2 dehydrogenase activity, methyltransferase activity, precorrin-4 C11-methyltransferase activity
Cellular Location: Cytoplasmic
KEGG Pathways:
  • adenosylcobalamin biosynthesis II (late cobalt incorporation) P381-PWY
  • cob(II)yrinate a,c-diamide biosynthesis II (late cobalt incorporation) PWY-7376
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    precorrin-4 + S-adenosyl-L-methionine → precorrin-5 + S-adenosyl-L-homocysteine + H+
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    precorrin-2 dehydrogenase activity
    methyltransferase activity
    precorrin-4 C11-methyltransferase activity
    Process
    cofactor biosynthetic process
    oxidation-reduction process
    metabolic process
    cobalamin biosynthetic process
    porphyrin-containing compound biosynthetic process
    Gene Properties
    Locus tag: PA2948
    Strand: +
    Entrez Gene ID: 882854
    Accession: NP_251638.1
    GI: 15598144
    Sequence start: 3307510
    Sequence End: 3308262
    Sequence Length: 752
    Gene Sequence: 
    >PA2948
ATGACCGTCTATTTCATCGGCGCCGGTCCCGGCGACCCTGACCTGATCACCGTCAAGGGGCAGCGCCTGATCCGCCAGTGCCCGGTGATCCTCTACGCCGGCTCGCTGGTTCCGCAAGCGCTGCTCGAGGGGCACCAGGCCGGCCAGGTGGTGAACACCGCCGAGCTGGACCTCGAACAGATCGTCGAGCTACTCGCGCAAGCCCATCGCCGCGGCCTCGACGTAGCCCGCGTGCATTCCGGCGATCCCTCCCTGTACGGCGCCATCGGCGAGCAGATCCGCCACCTGCGCGAACTCGGCATCCCCTATGAGATCGTCCCCGGGGTCACCGCCACCGCCGCCTGCGCCGCCCTGCTCGGCTGCGAGCTGACCCTGCCCGAAGTGTCCCAGACGCTGATCCTGACCCGCTACGCCGCACGCACGAAGATGCCGGAAGGCGAGAGCCTGGGCGACCTGGCGCGGCACCGGGCGACCCTGGCGATCCACCTGGGCGTCGCCCACCTGGCGAAGATCGTCGAGGAACTGCTGCCGCACTACGGCGCCGACTGCCCGGTCGCGGTGATCCACCGGGCCAGTTGGCCCGACCAGGAACAGGTTCGCGGCACCCTCGGCGACATCCTGCCCAAGGTCGCCGCCAGGAATTTCCGCCGCACCGCGCTGATCCTGGTCGGCGAGGTGCTGGCCGCCGAAGGCTTCGCCGACTCTTCGCTGTACCGCGCCGAGCATCGACATCTCTATCGACCCGGCGAATGA
    Protein Properties
    Protein Residues: 250
    Protein Molecular Weight: 27 kDa
    Protein Theoretical pI: 6.58
    Hydropathicity (GRAVY score): 0.085
    Charge at pH 7 (predicted): -2.48
    Protein Sequence: 
    >PA2948
MTVYFIGAGPGDPDLITVKGQRLIRQCPVILYAGSLVPQALLEGHQAGQVVNTAELDLEQIVELLAQAHRRGLDVARVHSGDPSLYGAIGEQIRHLRELGIPYEIVPGVTATAACAALLGCELTLPEVSQTLILTRYAARTKMPEGESLGDLARHRATLAIHLGVAHLAKIVEELLPHYGADCPVAVIHRASWPDQEQVRGTLGDILPKVAARNFRRTALILVGEVLAAEGFADSSLYRAEHRHLYRPGE
    References
    External Links:
    Resource Link
    Genome ID: PA2948
    Entrez Gene ID: 882854
    NCBI Protein ID: 15598144
    General Reference: PaperBLAST - Find papers about PA2948 and its homologs