Peptide methionine sulfoxide reductase msrB (PA2827)

Identification
Name: Peptide methionine sulfoxide reductase msrB
Synonyms:
  • Peptide-methionine (R)-S-oxide reductase
Gene Name: msrB
Enzyme Class:
Biological Properties
General Function: Involved in peptide-methionine-(S)-S-oxide reductase activity
Specific Function: Peptide-L-methionine + thioredoxin disulfide + H(2)O = peptide-L-methionine (R)-S-oxide + thioredoxin
Cellular Location: Not Available
KEGG Pathways: Not Available
KEGG Reactions:
Peptide-L-methionine+Thioredoxin disulfide+Thumb ↔ Peptide-L-methionine (R)-S-oxide+Thumb
Peptide-L-methionine + Thioredoxin disulfide + Water ↔ Peptide-L-methionine (R)-S-oxide + Thioredoxin
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Peptide-L-methionine+thioredoxin disulfide+Thumb → peptide-L-methionine (R)-S-oxide+thioredoxin
Peptide-L-methionine + thioredoxin disulfide + Water → peptide-L-methionine (R)-S-oxide + thioredoxin
ReactionCard
Peptide-L-methionine+Thioredoxin disulfide+Thumb ↔ Peptide-L-methionine (R)-S-oxide+Thumb
Peptide-L-methionine + Thioredoxin disulfide + Water ↔ Peptide-L-methionine (R)-S-oxide + Thioredoxin
ReactionCard
Protein-L-methionine+PAMDB000142 → Protein-L-methionine-R-S-oxides
Protein-L-methionine + Water → Protein-L-methionine-R-S-oxides
ReactionCard
Complex Reactions:
Thumb+Reduced Thioredoxin → Thumb+Thumb+Oxidized Thioredoxin
Methionine sulfoxide + Reduced Thioredoxin → Water + L-Methionine + Oxidized Thioredoxin
ReactionCard
Peptide-L-methionine+thioredoxin disulfide+Thumb → peptide-L-methionine (R)-S-oxide+thioredoxin
Peptide-L-methionine + thioredoxin disulfide + Water → peptide-L-methionine (R)-S-oxide + thioredoxin
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000175L-MethionineMetaboCard
PAMDB001133L-Methionine-(S)-S-oxideMetaboCard
PAMDB000428Methionine sulfoxideMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
catalytic activity
oxidoreductase activity
oxidoreductase activity, acting on a sulfur group of donors
oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
peptide-methionine-(S)-S-oxide reductase activity
Process
metabolic process
oxidation reduction
Gene Properties
Locus tag: PA2827
Strand: -
Entrez Gene ID: 878842
Accession: NP_251517.1
GI: 15598023
Sequence start: 3180554
Sequence End: 3180952
Sequence Length: 398
Gene Sequence: 
>PA2827
ATGAGCAAGATCGACAAACCCCTGGACTCCTGGCGCGAGGAGTTGACCGAAGAGCAGTTCCACATCTGTCGCCTGGGCGGTACCGAACGCGCCTTCAGTGGCGAATACCACGCCACCAAGACCCCCGGGATCTATCATTGCACCTGCTGCGGCACGGCGTTGTTCGACTCCGACGCCAAGTACGACTCCGGCAGCGGTTGGCCGAGCTATTTCCAGCCGGTGGACGCCGAGGCGGTCCGCGAACTGGACGACTTCAGCCACGGCATGCATCGCATCGAAGTCCGCTGCGGTCGCTGCGATGCCCACCTGGGGCACGTCTTCCCGGATGGCCCCCGGCCCACCGGGTTGCGTTACTGCATCAACTCGGCCTCGCTGAAGCTGGTGCCGCGGGAGAGCTAG
Protein Properties
Protein Residues: 132
Protein Molecular Weight: 14.8 kDa
Protein Theoretical pI: 6.14
Hydropathicity (GRAVY score): -0.582
Charge at pH 7 (predicted): -3.54
Protein Sequence: 
>PA2827
MSKIDKPLDSWREELTEEQFHICRLGGTERAFSGEYHATKTPGIYHCTCCGTALFDSDAKYDSGSGWPSYFQPVDAEAVRELDDFSHGMHRIEVRCGRCDAHLGHVFPDGPRPTGLRYCINSASLKLVPRES
References
External Links:
Resource Link
Genome ID: PA2827
Entrez Gene ID: 878842
NCBI Protein ID: 15598023
General Reference: PaperBLAST - Find papers about PA2827 and its homologs