Identification
Name: methylcrotonyl-CoA carboxylase, alpha-subunit (biotin-containing) alpha subunit of geranoyl-CoA carboxylase, GnyA; MccA
Synonyms: accA; mccA; gnyA
Gene Name: liuD
Enzyme Class: Not Available
Biological Properties
General Function: isoprenoid catabolic process, metabolic process, leucine catabolic process, terpene catabolic process
Specific Function: methylcrotonoyl-CoA carboxylase activity, biotin carboxylase activity, ATP binding, ligase activity, metal ion binding, catalytic activity, methylcrotonoyl-CoA carboxylase activity
Cellular Location: Cytoplasmic
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb
hydrogen carbonate + 3-methylcrotonyl-CoA + ATP → 3-methylglutaconyl-CoA + ADP + phosphate + H+
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites: Not Available
GO Classification:
Function
methylcrotonoyl-CoA carboxylase activity
biotin carboxylase activity
ATP binding
ligase activity
metal ion binding
catalytic activity
methylcrotonoyl-CoA carboxylase activity
Process
isoprenoid catabolic process
metabolic process
leucine catabolic process
terpene catabolic process
Gene Properties
Locus tag: PA2012
Strand: -
Entrez Gene ID: 879012
Accession: NP_250702.1
GI: 15597208
Sequence start: 2200685
Sequence End: 2202652
Sequence Length: 1967
Gene Sequence:
>PA2012
ATGAACCCGGACTACCGCAGCATCCAGCGCCTCCTGGTCGCCAACCGCGGCGAGATCGCCTGCCGGGTGATGCGCAGCGCGCGCGCCCTCGGCATCGGCAGCGTCGCCGTGCACAGCGACATCGACCGCCACGCCCGCCACGTCGCCGAAGCCGACATCGCCGTCGACCTGGGCGGCGCCAAGCCCGCCGACAGCTACCTGCGCGGCGACAGGATCATCGCAGCTGCCCTCGCCAGCGGCGCCCAGGCGATCCACCCCGGCTACGGCTTCCTCTCGGAGAACGCCGACTTCGCCCGCGCCTGCGAGGAAGCCGGCCTGCTCTTCCTCGGACCGCCGGCGGCGGCCATCGACGCCATGGGCAGCAAGTCGGCCGCCAAGGCGCTGATGGAAGAAGCCGGCGTGCCGCTGGTGCCCGGCTATCACGGCGAAGCCCAGGACCTCGAGACTTTCCGCCGGGAAGCCGGGCGCATCGGCTACCCGGTGCTGCTCAAGGCCGCCGCTGGCGGCGGCGGCAAGGGCATGAAGGTGGTGGAGCGCGAGGCCGAGCTGGCCGAGGCCCTTTCCTCCGCCCAGCGCGAGGCCAAGGCCGCCTTCGGCGACGCGCGTATGCTGGTGGAGAAATACCTGCTGAAGCCGCGCCACGTGGAGATCCAGGTATTCGCCGACCGCCATGGCCACTGCCTGTACCTCAACGAACGCGACTGTTCGATCCAGCGCCGCCACCAGAAGGTCGTCGAGGAAGCCCCCGCCCCCGGTCTCGGCGCGGAACTGCGCCGGGCCATGGGCGAGGCCGCGGTACGCGCGGCGCAGGCGATCGGCTACGTCGGCGCCGGTACCGTCGAATTCCTCCTCGACGAACGCGGCCAGTTCTTCTTCATGGAAATGAACACCCGCCTGCAGGTGGAACACCCGGTCACCGAGGCCATCACCGGCCTCGACCTGGTCGCCTGGCAGATCCGCGTCGCTCGCGGCGAGGCGCTACCGCTGACGCAGGAACAGGTACCGCTGAACGGCCACGCCATCGAAGTACGGCTCTATGCGGAAGACCCCGAGGGCGACTTCCTCCCCGCCAGCGGCCGCCTGATGCTATACCGCGAAGCGGCCGCCGGCCCCGGCCGGCGGGTCGACAGCGGGGTACGCGAAGGCGACGAGGTCTCGCCGTTCTACGACCCGATGCTGGCCAAGCTGATCGCCTGGGGCGAAACCCGCGAGGAAGCCCGCCAGCGCCTGCTGGCGATGCTGGCGGAAACCTCGGTCGGCGGCCTGCGCACCAACCTGGCGTTCCTCCGCCGCATCCTCGGCCATCCGGCGTTCGCCGCCGCCGAACTGGACACCGGGTTCATCGCGCGCCACCAAGACGACCTGCTGCCGGCGCCGCAAGCGCTGCCGGAGCATTTCTGGCAAGCCGCCGCCGAAGCCTGGCTGCAGAGCGAACCGGGCCACCGTCGCGACGACGACCCGCATTCGCCGTGGAGCCGCAACGACGGCTGGCGCAGCGCCCTGGCGCGGGAGTCCGACCTGATGCTGCGCTGCCGCGACGAACGCCGCTGCGTCCGCCTGCGCCACGCCAGCCCCAGCCAGTATCGCCTCGACGGCGACGACCTGGTCAGCCGGGTGGACGGTGTCACCCGTCGCTCGGCGGCGTTGCGCCGCGGACGCCAATTGTTCCTCGAATGGGAGGGCGAACTGCTGGCCATCGAAGCCGTCGACCCGATCGCCGAGGCCGAGGCCGCCCATGCCCACCAGGGCGGTTTGAGCGCGCCGATGAACGGCAGTATCGTGCGGGTCCTGGTCGAGCCCGGCCAGACGGTCGAAGCCGGCGCCACCCTGGTGGTGCTGGAGGCGATGAAGATGGAACACAGCATCCGCGCGCCCCACGCCGGGGTAGTGAAGGCGCTGTATTGCAGCGAGGGCGAACTGGTCGAGGAAGGCACGCCGCTGGTGGAGCTGGACGAGAACCAGGCCTGA
Protein Properties
Protein Residues: 655
Protein Molecular Weight: 71.3 kDa
Protein Theoretical pI: 5.62
Hydropathicity (GRAVY score): -0.234
Charge at pH 7 (predicted): -16.1
Protein Sequence:
>PA2012
MNPDYRSIQRLLVANRGEIACRVMRSARALGIGSVAVHSDIDRHARHVAEADIAVDLGGAKPADSYLRGDRIIAAALASGAQAIHPGYGFLSENADFARACEEAGLLFLGPPAAAIDAMGSKSAAKALMEEAGVPLVPGYHGEAQDLETFRREAGRIGYPVLLKAAAGGGGKGMKVVEREAELAEALSSAQREAKAAFGDARMLVEKYLLKPRHVEIQVFADRHGHCLYLNERDCSIQRRHQKVVEEAPAPGLGAELRRAMGEAAVRAAQAIGYVGAGTVEFLLDERGQFFFMEMNTRLQVEHPVTEAITGLDLVAWQIRVARGEALPLTQEQVPLNGHAIEVRLYAEDPEGDFLPASGRLMLYREAAAGPGRRVDSGVREGDEVSPFYDPMLAKLIAWGETREEARQRLLAMLAETSVGGLRTNLAFLRRILGHPAFAAAELDTGFIARHQDDLLPAPQALPEHFWQAAAEAWLQSEPGHRRDDDPHSPWSRNDGWRSALARESDLMLRCRDERRCVRLRHASPSQYRLDGDDLVSRVDGVTRRSAALRRGRQLFLEWEGELLAIEAVDPIAEAEAAHAHQGGLSAPMNGSIVRVLVEPGQTVEAGATLVVLEAMKMEHSIRAPHAGVVKALYCSEGELVEEGTPLVELDENQA
References
External Links:
Resource Link
Genome ID: PA2012
Entrez Gene ID: 879012
NCBI Protein ID: 15597208
General Reference: PaperBLAST - Find papers about PA2012 and its homologs