Para-aminobenzoate synthase component 1 (PA1758)

Identification
Name: Para-aminobenzoate synthase component 1
Synonyms:
  • ADC synthase
  • Para-aminobenzoate synthase component I
Gene Name: pabB
Enzyme Class:
Biological Properties
General Function: Involved in biosynthetic process
Specific Function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb
Chorismate + L-Glutamine ↔ 4-Amino-4-deoxychorismate + L-Glutamate
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb
Chorismate + L-Glutamine ↔ 4-Amino-4-deoxychorismate + L-Glutamate
ReactionCard
SMPDB Reactions:
Thumb+Thumb → L-Glutamic acid+4-amino-4-deoxychorismate+Thumb+Thumb
Chorismate + L-Glutamine → L-Glutamic acid + 4-amino-4-deoxychorismate + L-Glutamate + 4-Amino-4-deoxychorismate
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb
Chorismate + L-Glutamine ↔ 4-Amino-4-deoxychorismate + L-Glutamate
ReactionCard
Complex Reactions:
Thumb+Thumb → Thumb+Thumb
L-Glutamine + Water → L-Glutamate + Ammonium
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Thumb+Thumb → Thumb+Thumb
Chorismate + L-Glutamine → 4-Amino-4-deoxychorismate + L-Glutamate
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0009334-Amino-4-deoxychorismateMetaboCard
PAMDB001595AmmoniumMetaboCard
PAMDB000828ChorismateMetaboCard
PAMDB000055L-GlutamateMetaboCard
PAMDB000163L-GlutamineMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
carbon-carbon lyase activity
catalytic activity
lyase activity
oxo-acid-lyase activity
Process
biosynthetic process
cellular aromatic compound metabolic process
cellular metabolic process
folic acid and derivative biosynthetic process
folic acid and derivative metabolic process
metabolic process
Gene Properties
Locus tag: PA1758
Strand: -
Entrez Gene ID: 879428
Accession: NP_250449.1
GI: 15596955
Sequence start: 1897290
Sequence End: 1898651
Sequence Length: 1361
Gene Sequence: 
>PA1758
ATGCCCAGTTGTCATGTTCACCCCCTGCCCTACCATAGCGACCCAAGCTGTCTCTTTGCCATCATCCATGAGGCGCCCGGTGCGGTGATGCTCGATTCGGGTCGCCCCATCGCTACCCGTGGACGCTATGACCTTATGAGCGCCTGGCCATTGGCAGAACTGGCGCCGCTGCCCGACGAATCGGCCAACCGCTTCTTCGCCCGCCTACGCGAAGCGGCCGGAAGCCTGGGCCCCGCGCAGCTGCCAGCGCCGTACGAACTGCCCTTCGCCGGCGGTCTGCTGGGCTATTTATCCTACGACCTGGGTCGGCGCATCGAGCGCATCGGCGAACACGCCCGCGATGACCTGGGCCTGCCGCTGGCCTCCGTCGGCCTGTATGCCTGGGCGCTGATCAGCGACCACCAGGCCGGCACCAGCCAACTGGTATTCCACCCGCGATTGGACGAGCGCGAACGCCAGCGCCTGATCGCCCTGTTCAGCGAGGAAGCGCAAGGCACGGCCGGCAACTTCAAGCTTCTGGGAAAATTCCGACGGAGCATCAGCGCATCCGACTATCGGCAGGCGATCCGCCGCATCCAGGACTACATCCAGGCAGGCGACTGCTACCAGGTGAACTATAGCCAGCGCTTCCAGGCCGCTTGCAGCGGCTCGCCGTGGCCGGCCTATCGCGCCCTGCGCGAGGCCTGCCCGACGCCGTTCTCCGGCTACCTGCGACTGGCCGACGGCGCGATCCTCAGCCTGTCGCCGGAGCGCTTCCTCAAGCTCGGCAAGGGCAAGGTGGAAACCCGGCCGATCAAGGGCACCCGCCCGCGCGGCAAGACCCCCGAGGAGGACATGGCGCTGGCGGCGTCGCTGCTGGCCAGCCCCAAGGACCGCGCGGAAAACCTGATGATCGTCGACCTGCTGCGCAACGACATCGGACGCAGTTGCCAACCTGGCAGCGTACGGGTACCGGAGCTGTTTGCCCTGGAAAGCTATCCCAACGTGCATCACCTGGTGAGCAGCGTCACCGGCGAACTGGCGCCGGGCAAGGACGCCCTCGACCTGCTGGAAGGCAGCTTCCCCGGCGGCTCGATCACCGGCGCGCCGAAGATTCGCGCCATGCAGATCATCGACGAGCTGGAACCGAGCCGACGCGGCATCTACTGCGGCAGCCTGTTCTACCTCGACGTGCGCGGCGAGATGGACAGCTCGATCGCCATCCGCACCCTGCTGGTCAGGGACGGCCAGGTCAGTTGCTGGGGCGGCGGCGGCATCGTCGCCGACTCGCACTGGGAGGACGAGTACCAGGAAACCCTGGACAAGGTCCGGGTGCTGCTGGAAACCCTGGAAGGAATGGCCGGGACAGCGTCCCCGGAATAG
Protein Properties
Protein Residues: 453
Protein Molecular Weight: 49.6 kDa
Protein Theoretical pI: 6.2
Hydropathicity (GRAVY score): -0.225
Charge at pH 7 (predicted): -4.82
Protein Sequence: 
>PA1758
MPSCHVHPLPYHSDPSCLFAIIHEAPGAVMLDSGRPIATRGRYDLMSAWPLAELAPLPDESANRFFARLREAAGSLGPAQLPAPYELPFAGGLLGYLSYDLGRRIERIGEHARDDLGLPLASVGLYAWALISDHQAGTSQLVFHPRLDERERQRLIALFSEEAQGTAGNFKLLGKFRRSISASDYRQAIRRIQDYIQAGDCYQVNYSQRFQAACSGSPWPAYRALREACPTPFSGYLRLADGAILSLSPERFLKLGKGKVETRPIKGTRPRGKTPEEDMALAASLLASPKDRAENLMIVDLLRNDIGRSCQPGSVRVPELFALESYPNVHHLVSSVTGELAPGKDALDLLEGSFPGGSITGAPKIRAMQIIDELEPSRRGIYCGSLFYLDVRGEMDSSIAIRTLLVRDGQVSCWGGGGIVADSHWEDEYQETLDKVRVLLETLEGMAGTASPE
References
External Links:
Resource Link
Genome ID: PA1758
Entrez Gene ID: 879428
NCBI Protein ID: 15596955
General Reference: PaperBLAST - Find papers about PA1758 and its homologs