Identification
Name: probable 3-hydroxyisobutyrate dehydrogenase
Synonyms: Not Available
Gene Name: Not Available
Enzyme Class: Not Available
Biological Properties
General Function: oxidation-reduction process, valine metabolic process, pentose-phosphate shunt
Specific Function: oxidoreductase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, coenzyme binding, 3-hydroxyisobutyrate dehydrogenase activity, NAD binding, phosphogluconate dehydrogenase (decarboxylating) activity
Cellular Location: Cytoplasmic
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb
(S)-3-hydroxy-isobutanoate + NAD+ → (S)-methylmalonate-semialdehyde + NADH + H+
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites: Not Available
GO Classification:
Function
oxidoreductase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
coenzyme binding
3-hydroxyisobutyrate dehydrogenase activity
NAD binding
phosphogluconate dehydrogenase (decarboxylating) activity
Process
oxidation-reduction process
valine metabolic process
pentose-phosphate shunt
Gene Properties
Locus tag: PA1576
Strand: +
Entrez Gene ID: 881949
Accession: NP_250267.1
GI: 15596773
Sequence start: 1715809
Sequence End: 1716675
Sequence Length: 866
Gene Sequence:
>PA1576
ATGACTGCGGTCGCATTTCTCGGCCTGGGCACGATGGGCTACCCGATGGCCGGGCACCTGCAACGAGAGGGCTACGACGTCTGTGTCTACAATCGCTCGTCGGCCAAGGCGCTGCGCTGGGTCGAGGAGTACGCCGGACGGCGCGCCGATACGCCGCGCGAGGCCTGTGCTGGCGCCGAGCTGGTGTTCTGTTGCGTCGGTAACGACGACGACCTGCGTGCCGTGGCGCTGGGCGAGCAGGGCGCCTTCGCCGGAATGGCGCCGGGCAGCCTGTTCGTCGACCACACCACCGCTTCGGCGGAAGTCGCCCGCGAGCTGTCGCTGCTGGCTGCCGAGCGTGAGCTGGGCTTTCTCGACGCGCCGGTCTCCGGCGGCCAGGCAGGCGCGGTCAACGGCGCCCTGACGGTGATGGTCGGTGGCGAGGAGGCCTTCTATCGACGCGCCGAACCGCTGTTGCGCAGCTATGCGCGGATGGTCCGGCGAATGGGCGACGTGGGTAGCGGGCAATTGACCAAGATGGTCAACCAGATCTGCGTCGCGGGGCTGCTCCAGGGCCTGGCCGAGGCGCTGCACTTCGCCCGGTGCGCCGGTCTCGATGGCGAGGCGGCGATGCAGGTGATCGGCAAGGGCGCGGCCCAGTCCTGGCAACTGGAAAACCGCCACCAGAGCATGCTGGCCGGAGAGTTCGACTTCGGCTTCGCCGTGGACTGGATGCGCAAGGACCTGTCGATCCTGCTCGCCGAGGCGCGGCGCAACGGCGCGCAGTTGCCGGTCACGGCGCTGGTCGACCAGTTCTACGCCGAAGTGCAGGCGATGGGCGGCGGTCGTTGGGATACCTCCAGCCTGATCGCCCGGCTGCGTTCGTGA
Protein Properties
Protein Residues: 288
Protein Molecular Weight: 30.8 kDa
Protein Theoretical pI: 5.18
Hydropathicity (GRAVY score): 0.036
Charge at pH 7 (predicted): -5.22
Protein Sequence:
>PA1576
MTAVAFLGLGTMGYPMAGHLQREGYDVCVYNRSSAKALRWVEEYAGRRADTPREACAGAELVFCCVGNDDDLRAVALGEQGAFAGMAPGSLFVDHTTASAEVARELSLLAAERELGFLDAPVSGGQAGAVNGALTVMVGGEEAFYRRAEPLLRSYARMVRRMGDVGSGQLTKMVNQICVAGLLQGLAEALHFARCAGLDGEAAMQVIGKGAAQSWQLENRHQSMLAGEFDFGFAVDWMRKDLSILLAEARRNGAQLPVTALVDQFYAEVQAMGGGRWDTSSLIARLRS
References
External Links:
Resource Link
Genome ID: PA1576
Entrez Gene ID: 881949
NCBI Protein ID: 15596773
General Reference: PaperBLAST - Find papers about PA1576 and its homologs