Identification
Name: guanidinobutyrase agmatinase, agmatine ureohydrolase, AUH, proclavaminate amidino hydrolase, proclavaminic acid amidino hydrolase, PAH; 4-guanidinobutanoate amidinohydrolase
Synonyms: speB2
Gene Name: gbuA
Enzyme Class: Not Available
Biological Properties
General Function: arginine catabolic process
Specific Function: guanidinobutyrase activity, metal ion binding, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
Cellular Location: Cytoplasmic
KEGG Pathways:
  • superpathway of L-arginine, putrescine, and 4-aminobutyrate degradation ARGDEG-PWY
  • superpathway of polyamine biosynthesis I POLYAMSYN-PWY
  • L-arginine degradation III (arginine decarboxylase/agmatinase pathway) PWY0-823
  • putrescine biosynthesis I PWY-40
  • L-arginine degradation IX (arginine:pyruvate transaminase pathway) PWY-5742
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    4-guanidinobutanoate + H2O → urea + 4-aminobutanoate
    ReactionCard
    Thumb
    agmatine + H2O → urea + putrescine
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    guanidinobutyrase activity
    metal ion binding
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
    Process
    arginine catabolic process
    Gene Properties
    Locus tag: PA1421
    Strand: -
    Entrez Gene ID: 881747
    Accession: NP_250112.1
    GI: 15596618
    Sequence start: 1546271
    Sequence End: 1547230
    Sequence Length: 959
    Gene Sequence:
    >PA1421
    GTGGACAAGAATCTCCACCAGCCCCTGGGCGGCAATGAAATGCCCCGCTTCGGCGGCATCGCCACCATGATGCGCCTGCCCCATGTCCAGTCCCCCGCCGAACTCGACGCCCTCGATGCCGCCTTCGTCGGCGTGCCCCTCGACATCGGCACCTCCCTGCGCTCCGGTACCCGCTTCGGCCCCCGCGAGATCCGCGCCGAATCGGTGATGATCCGTCCCTACAACATGGCCACCGGCGCCGCCCCCTTCGACTCGCTGAACGTGGCGGACATCGGCGACGTCGCGATCAACACCTTCAACCTGCTGGAAGCCGTGCGCATCATCGAGCAGGAATACGACCGCATCCTCGGTCACGGCATCCTCCCGCTGACCCTCGGCGGCGACCACACCATCACCCTGCCGATCCTCCGCGCGATCAAGAAGAAGCACGGCAAGGTCGGCCTGGTCCACGTCGACGCCCACGCCGACGTCAACGACCACATGTTCGGCGAGAAGATCGCCCACGGCACCACCTTCCGCCGCGCGGTGGAAGAAGACCTGCTGGATTGCGACCGTGTTGTGCAGATCGGCCTGCGCGCCCAGGGCTACACCGCCGAGGACTTCAACTGGAGCCGCAAGCAGGGCTTCCGCGTGGTGCAGGCCGAGGAGTGCTGGCACAAGTCGCTGGAGCCGCTGATGGCCGAGGTCCGCGAGAAGGTCGGCGGCGGCCCCGTCTACCTGAGCTTCGACATCGACGGCATCGACCCGGCCTGGGCGCCCGGCACCGGCACCCCGGAAATCGGCGGCCTGACCACCATCCAGGCGATGGAAATCATCCGCGGCTGCCAGGGCCTGGACCTGATCGGCTGCGACCTGGTCGAAGTCTCGCCGCCCTACGACACCACCGGCAACACTTCGTTGCTGGGCGCCAACCTGCTCTATGAAATGCTCTGCGTCCTCCCGGGCGTGGTGCGTCGCTGA
    Protein Properties
    Protein Residues: 319
    Protein Molecular Weight: 34.7 kDa
    Protein Theoretical pI: 5.07
    Hydropathicity (GRAVY score): -0.039
    Charge at pH 7 (predicted): -10.74
    Protein Sequence:
    >PA1421
    MDKNLHQPLGGNEMPRFGGIATMMRLPHVQSPAELDALDAAFVGVPLDIGTSLRSGTRFGPREIRAESVMIRPYNMATGAAPFDSLNVADIGDVAINTFNLLEAVRIIEQEYDRILGHGILPLTLGGDHTITLPILRAIKKKHGKVGLVHVDAHADVNDHMFGEKIAHGTTFRRAVEEDLLDCDRVVQIGLRAQGYTAEDFNWSRKQGFRVVQAEECWHKSLEPLMAEVREKVGGGPVYLSFDIDGIDPAWAPGTGTPEIGGLTTIQAMEIIRGCQGLDLIGCDLVEVSPPYDTTGNTSLLGANLLYEMLCVLPGVVRR
    References
    External Links:
    Resource Link
    Genome ID: PA1421
    Entrez Gene ID: 881747
    NCBI Protein ID: 15596618
    General Reference: PaperBLAST - Find papers about PA1421 and its homologs