| Identification |
| Name: |
alkaline metalloproteinase precursor |
| Synonyms: |
Not Available |
| Gene Name: |
aprA |
| Enzyme Class: |
Not Available |
| Biological Properties |
| General Function: |
proteolysis, positive regulation of sodium ion transport, pathogenesis, negative regulation of complement activation, lectin pathway, negative regulation of complement activation, classical pathway |
| Specific Function: |
metalloendopeptidase activity, peptidase activity, metallopeptidase activity, zinc ion binding, calcium ion binding |
| Cellular Location: |
Extracellular |
| KEGG Pathways: |
|
| KEGG Reactions: |
Not Available |
| SMPDB Reactions: |
Not Available |
| PseudoCyc/BioCyc Reactions: |
|
| Complex Reactions: |
Not Available |
| Transports: |
Not Available |
| Metabolites: |
Not Available |
| GO Classification: |
| Component |
|---|
| extracellular space | | Function |
|---|
| metalloendopeptidase activity | | peptidase activity | | metallopeptidase activity | | zinc ion binding | | calcium ion binding | | Process |
|---|
| proteolysis | | positive regulation of sodium ion transport | | pathogenesis | | negative regulation of complement activation, lectin pathway | | negative regulation of complement activation, classical pathway |
|
| Gene Properties |
| Locus tag: |
PA1249 |
| Strand: |
+ |
| Entrez Gene ID: |
881248 |
| Accession: |
NP_249940.1 |
| GI: |
15596446 |
| Sequence start: |
1355631 |
| Sequence End: |
1357070 |
| Sequence Length: |
1439 |
| Gene Sequence: |
>PA1249
ATGTCCAGCAATTCTCTTGCATTGAAAGGTCGTAGCGATGCGTATACCCAGGTAGACAACTTCCTGCATGCCTATGCGCGGGGCGGGGACGAATTGGTCAATGGCCATCCGTCCTATACCGTCGACCAGGCGGCGGAGCAGATCCTCCGCGAACAGGCGTCTTGGCAGAAAGCGCCGGGCGACTCGGTGCTGACCCTGTCCTATTCGTTCCTGACCAAACCGAACGACTTCTTCAATACGCCGTGGAAGTATGTCAGCGATATCTACTCGCTGGGCAAGTTCAGCGCCTTTTCCGCGCAGCAGCAGGCCCAGGCCAAGTTGTCGCTGCAATCCTGGTCGGACGTCACCAATATCCACTTCGTCGACGCCGGCCAGGGCGATCAGGGCGACCTGACCTTCGGCAACTTCAGCAGTAGTGTCGGCGGTGCGGCGTTCGCCTTCCTGCCGGATGTACCGGATGCGCTCAAGGGGCAATCCTGGTACCTGATCAACAGCAGCTACAGCGCCAACGTCAATCCGGCCAACGGCAACTACGGACGCCAGACCCTGACCCACGAGATCGGCCATACCCTGGGCCTGAGCCACCCCGGCGACTACAACGCCGGCGAGGGCGATCCCACCTACGCCGACGCTACCTACGCCGAGGACACCCGCGCCTATTCGGTGATGAGCTACTGGGAAGAGCAGAACACCGGCCAGGACTTCAAGGGCGCCTATTCCTCGGCACCGCTGCTGGACGACATCGCGGCGATCCAGAAGCTCTACGGGGCCAACCTGACCACTCGCACCGGCGACACGGTGTACGGCTTCAACTCCAACACCGAGCGCGACTTCTACAGCGCCACCTCGTCCAGTTCCAAGCTGGTGTTCTCGGTGTGGGACGCCGGCGGCAACGACACCCTGGACTTCTCCGGCTTCAGCCAGAACCAGAAGATCAACCTCAACGAGAAGGCGCTGTCCGATGTCGGCGGGTTGAAGGGCAATGTGTCGATCGCTGCCGGGGTCACCGTGGAAAACGCCATCGGCGGCTCGGGTAGCGACCTGTTGATCGGCAACGACGTGGCCAACGTGCTCAAGGGCGGCGCCGGCAACGACATCCTCTACGGCGGCCTCGGCGCGGACCAGCTGTGGGGTGGCGCGGGAGCCGACACCTTCGTCTACGGCGATATCGCCGAGTCCTCCGCGGCGGCGCCGGATACCCTGCGCGACTTCGTCAGCGGCCAGGACAAGATCGACCTGTCCGGGCTGGACGCCTTCGTCAACGGCGGGCTGGTGCTGCAATACGTCGACGCCTTCGCCGGCAAGGCCGGCCAGGCGATCCTGTCCTACGACGCGGCGAGCAAGGCCGGCAGCCTGGCGATCGACTTCAGCGGGGACGCCCATGCCGATTTCGCGATCAATCTGATCGGCCAGGCGACCCAGGCCGACATCGTCGTCTGA |
| Protein Properties |
| Protein Residues: |
479 |
| Protein Molecular Weight: |
50.4 kDa |
| Protein Theoretical pI: |
4.09 |
| Hydropathicity (GRAVY score): |
-0.223 |
| Charge at pH 7 (predicted): |
-28.31 |
| Protein Sequence: |
>PA1249
MSSNSLALKGRSDAYTQVDNFLHAYARGGDELVNGHPSYTVDQAAEQILREQASWQKAPGDSVLTLSYSFLTKPNDFFNTPWKYVSDIYSLGKFSAFSAQQQAQAKLSLQSWSDVTNIHFVDAGQGDQGDLTFGNFSSSVGGAAFAFLPDVPDALKGQSWYLINSSYSANVNPANGNYGRQTLTHEIGHTLGLSHPGDYNAGEGDPTYADATYAEDTRAYSVMSYWEEQNTGQDFKGAYSSAPLLDDIAAIQKLYGANLTTRTGDTVYGFNSNTERDFYSATSSSSKLVFSVWDAGGNDTLDFSGFSQNQKINLNEKALSDVGGLKGNVSIAAGVTVENAIGGSGSDLLIGNDVANVLKGGAGNDILYGGLGADQLWGGAGADTFVYGDIAESSAAAPDTLRDFVSGQDKIDLSGLDAFVNGGLVLQYVDAFAGKAGQAILSYDAASKAGSLAIDFSGDAHADFAINLIGQATQADIVV |
| References |
| External Links: |
|
| General Reference: |
PaperBLAST - Find papers about PA1249 and its homologs
|
