Identification |
Name: |
Ribosomal RNA small subunit methyltransferase A |
Synonyms: |
- 16S rRNA dimethyladenosine transferase
- 16S rRNA dimethylase
- High level kasugamycin resistance protein ksgA
- Kasugamycin dimethyltransferase
- S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase
|
Gene Name: |
rsmA |
Enzyme Class: |
|
Biological Properties |
General Function: |
Translation, ribosomal structure and biogenesis |
Specific Function: |
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Has also a DNA glycosylase/AP lyase activity that removes C mispaired with oxidized T from DNA, and may play a role in protection of DNA against oxidative stress |
Cellular Location: |
Cytoplasm (Potential) |
KEGG Pathways: |
|
KEGG Reactions: |
Not Available |
SMPDB Reactions: |
Not Available |
PseudoCyc/BioCyc Reactions: |
|
Complex Reactions: |
Not Available |
Transports: |
Not Available |
Metabolites: |
PAMDB ID | Name | View |
---|
PAMDB000205 | S-Adenosylhomocysteine | MetaboCard | PAMDB000289 | S-Adenosylmethionine | MetaboCard |
|
GO Classification: |
Function |
---|
catalytic activity | methyltransferase activity | N-methyltransferase activity | RNA methyltransferase activity | rRNA (adenine) methyltransferase activity | rRNA (adenine-N6,N6-)-dimethyltransferase activity | rRNA methyltransferase activity | transferase activity | transferase activity, transferring one-carbon groups | Process |
---|
cellular macromolecule metabolic process | macromolecule metabolic process | metabolic process | ncRNA metabolic process | RNA metabolic process | rRNA metabolic process | rRNA modification | rRNA processing |
|
Gene Properties |
Locus tag: |
PA0905 |
Strand: |
+ |
Entrez Gene ID: |
878352 |
Accession: |
NP_249596.1 |
GI: |
15596102 |
Sequence start: |
991013 |
Sequence End: |
991198 |
Sequence Length: |
185 |
Gene Sequence: |
>PA0905
ATGCTGATTCTGACTCGTCGGGTCGGAGAGACCCTGATGGTAGGTGACGACGTCACCGTGACGGTACTGGGTGTCAAAGGGAACCAGGTGCGCATCGGCGTCAACGCGCCGAAGGAAGTCGCCGTACACCGGGAGGAAATTTACCAGCGCATCCAGAAAGAGAAAGATCAAGAGCCAAACCATTAA |
Protein Properties |
Protein Residues: |
61 |
Protein Molecular Weight: |
6.9 kDa |
Protein Theoretical pI: |
7.7 |
Hydropathicity (GRAVY score): |
-0.446 |
Charge at pH 7 (predicted): |
0.46 |
Protein Sequence: |
>PA0905
MLILTRRVGETLMVGDDVTVTVLGVKGNQVRIGVNAPKEVAVHREEIYQRIQKEKDQEPNH |
References |
External Links: |
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General Reference: |
PaperBLAST - Find papers about PA0905 and its homologs
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