Lysine-sensitive aspartokinase 3 (PA0904)

Identification
Name: Lysine-sensitive aspartokinase 3
Synonyms:
  • Aspartate kinase III
  • AKIII
  • Lysine-sensitive aspartokinase III
Gene Name: lysC
Enzyme Class:
Biological Properties
General Function: Involved in amino acid binding
Specific Function: ATP + L-aspartate = ADP + 4-phospho-L- aspartate
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb
L-Aspartic acid + Adenosine triphosphate ↔ L-Aspartyl-4-phosphate + ADP
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb
Adenosine triphosphate + L-Aspartic acid ↔ ADP + L-Aspartyl-4-phosphate
ReactionCard
SMPDB Reactions:
L-Aspartic acid+Thumb+Thumb → Adenosine diphosphate+Thumb+Thumb
L-Aspartic acid + Adenosine triphosphate + L-Aspartic acid → Adenosine diphosphate + L-Aspartyl-4-phosphate + ADP
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb
L-Aspartic acid + Adenosine triphosphate ↔ L-Aspartyl-4-phosphate + ADP
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
PAMDB000080L-Aspartic acidMetaboCard
PAMDB000834L-Aspartyl-4-phosphateMetaboCard
GO Classification:
Function
amino acid binding
aspartate kinase activity
binding
carboxylic acid binding
catalytic activity
phosphotransferase activity, carboxyl group as acceptor
transferase activity
transferase activity, transferring phosphorus-containing groups
Process
biosynthetic process
cellular amino acid and derivative metabolic process
cellular amino acid biosynthetic process
cellular amino acid metabolic process
cellular metabolic process
metabolic process
Gene Properties
Locus tag: PA0904
Strand: +
Entrez Gene ID: 878315
Accession: NP_249595.1
GI: 15596101
Sequence start: 989590
Sequence End: 990828
Sequence Length: 1238
Gene Sequence: 
>PA0904
ATGGCTTTGATCGTACAGAAGTTTGGAGGGACCTCCGTCGGCACCGTCGAGCGTATCGAGCAGGTGGCCGAGAAGGTGAAGAAATTCCGCGAAGCGGGCGATGACGTCGTCGTGGTGGTATCCGCCATGAGCGGGGAGACCAACCGTCTGATCGGCCTGGCCAACCAGATCATGGAGCAGCCGGTTCCGCGCGAACTGGACGTCATGGTCTCGACCGGAGAGCAGGTGACCATCGCCCTGCTCAGCATGGCCCTGATCAAGCGCGGCGTGCCGGCGGTCTCCTATACCGGCAACCAGGTGCGTATCCTCACCGACAGCGCGCACACCAAGGCGCGCATCCTGCACATCGACGACACCCACATCCGCGCCGACCTCAAGGCCGGCAGGGTAGTGGTGGTCGCCGGTTTCCAGGGCGTCGACGGCAACGGCAACATCACCACGCTGGGCCGCGGCGGTTCCGATACCACCGGGGTGGCCCTGGCGGCGGCGTTGAAGGCCGACGAATGCCAGATCTACACCGACGTCGACGGCGTCTACACCACCGATCCGCGCGTAGTGCCGCAGGCCCGTCGGCTGGACAAGATCACCTTCGAGGAAATGCTGGAAATGGCCAGCCTCGGTTCCAAGGTGCTGCAGATCCGGGCGGTCGAGTTCGCCGGCAAGTACAACGTTCCGCTGCGCGTGCTGCACAGCTTCCAGGAGGGTCCGGGCACCCTCATTACTATCGATGATGAAGAGGAATCCATGGAACAGCCGATCATCTCCGGCATCGCCTTCAACCGCGACGAAGCCAAGCTGACCATCCGTGGCGTACCCGATACCCCCGGCGTGGCCTTCAAGATCCTCGGGCCGATCAGTGCCGCCAATGTGGAAGTCGACATGATCGTGCAGAACGTGGCGCACGATAACACCACCGACTTCACCTTCACGGTGCATCGCAACGATTACCTGAACGCCCTGGAAATCCTCAAGCAGACCGCCGCCAACATCGGCGCGCGCGAAGCCATCGGCGACACCAACATCGCCAAGGTTTCCATCGTCGGCGTCGGCATGCGTTCGCACGCCGGCGTGGCCAGCCGCATGTTCGAAGCGCTGGCCAAGGAAAGCATCAACATCCAGATGATCTCCACCTCGGAAATCAAGGTTTCCGTGGTGATCGAAGAGAAGTACCTGGAACTGGCGGTACGTGCTCTGCACACGGCGTTCGAGCTCGACGCGCCGGCGCGACAGGGTGAGTGA
Protein Properties
Protein Residues: 412
Protein Molecular Weight: 44.4 kDa
Protein Theoretical pI: 4.99
Hydropathicity (GRAVY score): 0.043
Charge at pH 7 (predicted): -11.08
Protein Sequence: 
>PA0904
MALIVQKFGGTSVGTVERIEQVAEKVKKFREAGDDVVVVVSAMSGETNRLIGLANQIMEQPVPRELDVMVSTGEQVTIALLSMALIKRGVPAVSYTGNQVRILTDSAHTKARILHIDDTHIRADLKAGRVVVVAGFQGVDGNGNITTLGRGGSDTTGVALAAALKADECQIYTDVDGVYTTDPRVVPQARRLDKITFEEMLEMASLGSKVLQIRAVEFAGKYNVPLRVLHSFQEGPGTLITIDDEEESMEQPIISGIAFNRDEAKLTIRGVPDTPGVAFKILGPISAANVEVDMIVQNVAHDNTTDFTFTVHRNDYLNALEILKQTAANIGAREAIGDTNIAKVSIVGVGMRSHAGVASRMFEALAKESINIQMISTSEIKVSVVIEEKYLELAVRALHTAFELDAPARQGE
References
External Links:
Resource Link
Genome ID: PA0904
Entrez Gene ID: 878315
NCBI Protein ID: 15596101
General Reference: PaperBLAST - Find papers about PA0904 and its homologs