Identification
Name: hemolytic phospholipase C precursor sphingomyelin synthase
Synonyms: phlC; plcS
Gene Name: plcH
Enzyme Class: Not Available
Biological Properties
General Function: lipid catabolic process, protein secretion by the type II secretion system, protein transport by the Tat complex, interaction with host via protein secreted by type II secretion system, hemolysis in other organism, hemolysis in other organism, pathogenesis, pathogenesis, pathogenesis, pathogenesis, pathogenesis, pathogenesis
Specific Function: phospholipase C activity, hydrolase activity, acting on ester bonds, phosphatidylcholine phospholipase C activity, lipase activity, sphingomyelin synthase activity
Cellular Location: Extracellular
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Component
    extracellular space
    extracellular space
    extracellular space
    Function
    phospholipase C activity
    hydrolase activity, acting on ester bonds
    phosphatidylcholine phospholipase C activity
    lipase activity
    sphingomyelin synthase activity
    Process
    lipid catabolic process
    protein secretion by the type II secretion system
    protein transport by the Tat complex
    interaction with host via protein secreted by type II secretion system
    hemolysis in other organism
    hemolysis in other organism
    pathogenesis
    pathogenesis
    pathogenesis
    pathogenesis
    pathogenesis
    pathogenesis
    Gene Properties
    Locus tag: PA0844
    Strand: -
    Entrez Gene ID: 879296
    Accession: NP_249535.1
    GI: 15596041
    Sequence start: 919258
    Sequence End: 921450
    Sequence Length: 2192
    Gene Sequence:
    >PA0844
    ATGACCGAAAACTGGAAATTCCGCCGTCGAACCTTTCTCAAGCACGGCGCCCAGGCCGCTACCCTGGCCGGCCTTTCCGGGCTGTTCCCGGAGACGCTCCGGCGCGCCCTGGCCGTCGAGCCGGACATCCGCACCGGAACCATCCAGGACGTCCAGCACGTGGTCATCCTGATGCAGGAGAACCGCAGCTTCGATCACTACTTCGGCCACCTCAACGGCGTCCGCGGCTTCAACGACCCTCGCGCGCTCAAGCGCCAGGACGGCAAGCCGGTCTGGTACCAGAACTACAAGTACGAGTTCTCCCCCTATCACTGGGATACCAAGGTCACCAGCGCCCAGTGGGTGAGTTCGCAGAACCATGAATGGTCGGCCTTCCACGCGATCTGGAACCAGGGCCGCAACGACAAGTGGATGGCGGTGCAGTACCCCGAAGCCATGGGCTACTTCAAGCGCGGCGACATTCCCTACTACTACGCCCTGGCCGACGCCTTCACCCTGTGCGAGGCCTACCACCAGTCGATGATGGGCCCGACCAATCCGAACCGCCTCTACCACATGAGCGGACGCGCCGCCCCCAGCGGCGACGGCAAGGACGTACACATCGGCAACGACATGGGCGACGGCACCATCGGCGCCAGCGGCACGGTGGACTGGACCACCTATCCCGAGCGGCTAAGCGCCGCTGGCGTGGACTGGCGGGTCTACCAGGAAGGCGGCTACCGCTCCTCGTCACTCTGGTACCTGTACGTCGACGCCTACTGGAAATACCGGCTCCAGGAGCAGAACAACTACGACTGCAACGCCCTCGCCTGGTTCAGGAACTTCAAGAACGCTCCGCGCGATTCGGACCTCTGGCAGCGCGCCATGCTCGCCCGCGGCGTCGACCAGTTGCGCAAGGATGTGCAGGAGAACACGCTGCCGCAGGTGTCGTGGATCGTCGCGCCCTACTGCTACTGCGAGCATCCCTGGTGGGGCCCCTCGTTCGGCGAGTACTACGTGACCCGGGTGCTCGAGGCGCTGACCAGCAACCCCGAGGTCTGGGCCAGGACCGTGTTCATCCTCAACTACGACGAGGGCGACGGCTTCTATGACCACGCCAGCGCCCCGGTGCCGCCGTGGAAGGATGGCGTCGGCCTTTCCACGGTCAGCACCGCCGGCGAGATCGAGGTATCCAGCGGGCTGCCCATCGGGCTCGGCCACCGCGTCCCGCTGATCGCCATCTCGCCCTGGTCGAAGGGCGGCAAGGTCAGCGCCGAAGTGTTCGACCATACCTCGGTGCTGCGCTTCCTCGAACGCCGCTTCGGCGTCGTCGAGGAAAACATCTCGCCCTGGCGGCGTGCCGTCTGCGGCGACCTGACTTCGCTGTTCGACTTCCAGGGCGCAGGCGATACCCAGGTCGCCCCCGACCTGACCAACGTCCCGCAGAGCGACGCGCGCAAGGAGGACGCCTACTGGCAGCAGTTCTACCGGCCCAGTCCCAAATACTGGTCCTACGAGCCCAAGAGCCTGCCCGGCCAGGAAAAGGGCCAGCGCCCTACCCTCGCGGTGCCCTACCAGTTGCACGCCACGCTGGCCCTCGACATCGCCGCCGGCAAGCTGCGCCTGACCCTGGGCAACGACGGCATGAGCCTGCCGGGCAATCCGCAGGGACACTCCGCTGCGGTATTCCAGGTGCAGCCGCGGGAAGTCGGCAATCCGCGCTTCTATACCGTGACCAGCTATCCGGTGGTCCAGGAAAGCGGAGAGGAACTGGGCCGGACCCTCAACGACGAACTCGACGACCTGCTCGACGCCAACGGCCGCTACGCCTTCGAGGTGCACGGCCCCAACGGCTTCTTCCGCGAGTTCCACGGCAACCTGCATCTCGCCGCGCAGATGGCGCGGCCCGAGGTATCGGTCACCTATCAACGCAACGGCAACCTGCAGTTGAACATCCGCAATCTCGGCCGCCTGCCGTGCAGCGTGACGGTGACGCCGAACCCGGCCTATACCCGGGAGGGCAGCCGTCGCTATGAACTCGAACCGAACCAGGCGATCAGTGAAGTGTGGCTGTTACGCAGCAGCCAGGGCTGGTACGACCTCAGCGTGACCGCCAGCAATACGGAAGCCAACTATCTCCGCCGCCTGGCCGGACACGTCGAGACCGGCAAGCCGAGCAGGAGCGATCCATTGCTCGACATCGCAGCGACCTGA
    Protein Properties
    Protein Residues: 730
    Protein Molecular Weight: 82.7 kDa
    Protein Theoretical pI: 6.6
    Hydropathicity (GRAVY score): -0.548
    Charge at pH 7 (predicted): -4.35
    Protein Sequence:
    >PA0844
    MTENWKFRRRTFLKHGAQAATLAGLSGLFPETLRRALAVEPDIRTGTIQDVQHVVILMQENRSFDHYFGHLNGVRGFNDPRALKRQDGKPVWYQNYKYEFSPYHWDTKVTSAQWVSSQNHEWSAFHAIWNQGRNDKWMAVQYPEAMGYFKRGDIPYYYALADAFTLCEAYHQSMMGPTNPNRLYHMSGRAAPSGDGKDVHIGNDMGDGTIGASGTVDWTTYPERLSAAGVDWRVYQEGGYRSSSLWYLYVDAYWKYRLQEQNNYDCNALAWFRNFKNAPRDSDLWQRAMLARGVDQLRKDVQENTLPQVSWIVAPYCYCEHPWWGPSFGEYYVTRVLEALTSNPEVWARTVFILNYDEGDGFYDHASAPVPPWKDGVGLSTVSTAGEIEVSSGLPIGLGHRVPLIAISPWSKGGKVSAEVFDHTSVLRFLERRFGVVEENISPWRRAVCGDLTSLFDFQGAGDTQVAPDLTNVPQSDARKEDAYWQQFYRPSPKYWSYEPKSLPGQEKGQRPTLAVPYQLHATLALDIAAGKLRLTLGNDGMSLPGNPQGHSAAVFQVQPREVGNPRFYTVTSYPVVQESGEELGRTLNDELDDLLDANGRYAFEVHGPNGFFREFHGNLHLAAQMARPEVSVTYQRNGNLQLNIRNLGRLPCSVTVTPNPAYTREGSRRYELEPNQAISEVWLLRSSQGWYDLSVTASNTEANYLRRLAGHVETGKPSRSDPLLDIAAT
    References
    External Links:
    Resource Link
    Genome ID: PA0844
    Entrez Gene ID: 879296
    NCBI Protein ID: 15596041
    General Reference: PaperBLAST - Find papers about PA0844 and its homologs