| Identification |
| Name: |
Sodium/proline symporter |
| Synonyms: |
- Proline permease
- Propionate transporter
|
| Gene Name: |
putP |
| Enzyme Class: |
Not Available |
| Biological Properties |
| General Function: |
Involved in proline:sodium symporter activity |
| Specific Function: |
Catalyzes the sodium-dependent uptake of extracellular L-proline. This protein is also capable of using lithium as the transport cation. Also catalyzes the uptake of propionate |
| Cellular Location: |
Cell inner membrane; Multi-pass membrane protein |
| KEGG Pathways: |
|
| KEGG Reactions: |
Not Available |
| SMPDB Reactions: |
Not Available |
| PseudoCyc/BioCyc Reactions: |
| Na +[periplasm] + L-proline [periplasm] → Na +[cytosol] + L-proline [cytosol]ReactionCard |
|
| Complex Reactions: |
Not Available |
| Transports: |
|
| Metabolites: |
|
| GO Classification: |
| Component |
|---|
| cell part | | integral to membrane | | intrinsic to membrane | | membrane | | membrane part | | Function |
|---|
| alkali metal ion binding | | binding | | cation binding | | ion binding | | metal ion binding | | organic acid transmembrane transporter activity | | organic acid:sodium symporter activity | | proline:sodium symporter activity | | sodium ion binding | | sodium:amino acid symporter activity | | substrate-specific transmembrane transporter activity | | transmembrane transporter activity | | transporter activity | | Process |
|---|
| amine transport | | amino acid transport | | cation transport | | establishment of localization | | ion transport | | monovalent inorganic cation transport | | neutral amino acid transport | | proline transport | | sodium ion transport | | transmembrane transport | | transport |
|
| Gene Properties |
| Locus tag: |
PA0783 |
| Strand: |
+ |
| Entrez Gene ID: |
877927 |
| Accession: |
NP_249474.1 |
| GI: |
15595980 |
| Sequence start: |
855277 |
| Sequence End: |
856797 |
| Sequence Length: |
1520 |
| Gene Sequence: |
>PA0783
ATGAGTGTCAATACGCCCACGCTGATCACCTTCGTGATCTACATCGCGGCCATGGTCCTGATCGGCCTGGCGGCATATCGCTCCACCAACAACTTCTCCGACTACATCCTCGGTGGCCGCAGCCTCGGCAGCTTCGTCACGGCGCTGTCCGCCGGCGCCTCCGATATGAGCGGCTGGCTGCTGATGGGCCTGCCCGGCGCGGTGTACCTGTCCGGCCTGTCCGAAAGCTGGATCGCCATCGGCCTGATCGTCGGCGCCTACCTCAACTGGCTGTTCGTCGCCGGCCGCCTGCGGGTGCAGACCGAGCACAACGGCAACGCGCTGACCCTGCCCGACTACTTCACCAACCGCTTCGAGGACAACAGCCGCCTGCTGCGGATCTTCTCGGCCCTGGTGATCCTGGTGTTCTTCACCATCTACTGCGCTTCCGGCATCGTCGCCGGTGCGCGCCTGTTCGAGAGCACCTTCGGCCTCTCCTACGAGACCGCGCTGTGGGCCGGCGCCGCGGCGACCATCGCCTACACCTTCATCGGTGGCTTCCTCGCGGTGAGCTGGACCGACACCGTGCAGGCCTCGCTGATGATCTTCGCGCTGATCCTCACCCCGGTGATCGTGATGCTCGCCACCGGCGGCGTCGAGCCGACCTTCACCGCCATCGAGCTGAAGGACGCGACCAGCTTCGACATGCTCAAGGGCGCCTCCTTCATCGGCGTGATCTCGCTGATGGCCTGGGGCCTGGGCTACTTCGGCCAGCCGCACATCCTGGCGCGCTTCATGGCCGCCGACTCGGTGAAATCGATCCCGGCCGCGCGCCGCATCTCCATGACCTGGATGATCCTCTGCCTCGGTGGCGCCGTGGCCGTGGGCTTCTTCGGCATCGCCTACTTCCAGGCGCATCCGGAGCAGGCCGGCGCGGTCAGCGAGAACCCCGAGCGGGTATTCATCGAGCTGGCCAAGATCCTGTTCAACCCGTGGATCGCCGGCGTGTTGCTGTCCGCCATCCTCGCCGCGGTCATGAGCACCCTGAGCTGCCAGCTGCTGGTCTGCTCCTCGGCGCTCACCGAGGACTTCTACAAGGCCTTCCTGCGCAAGGGCGCCAGCCAGCTGGAACTGGTCTGGGTCGGTCGCGCCATGGTGCTGCTGGTGGCGGTGATCGCCATCTGGCTGGCCTCCAACCCGGAAAACCGCGTGCTCGGCCTGGTGTCCTATGCCTGGGCCGGCTTCGGCGCCGCCTTCGGCCCGCTGGTGCTGTTCTCCCTGCTGTGGAAGCGGATGACCCGCAACGGCGCGCTGGCCGGCATGATCGTCGGCGCGGCGACGGTGATCCTGTGGAAGAACCTGTTGGGCTGGACCGGCCTGTACGAGATCATCCCCGGCTTCCTCTTCGCCAGCGTCGCCATCGTCGTCTTCAGCCTGCTCGGCAAGGCGCCTTCGACGAGCATGCTCAAGCGCTTCGACGATGCGGAGCAGGAGTACCGCGAGGCGCACCAGGGTTCCGCCGCTCCGGTAACCCAGCGCTGA |
| Protein Properties |
| Protein Residues: |
506 |
| Protein Molecular Weight: |
54.4 kDa |
| Protein Theoretical pI: |
7.93 |
| Hydropathicity (GRAVY score): |
0.749 |
| Charge at pH 7 (predicted): |
1.83 |
| Protein Sequence: |
>PA0783
MSVNTPTLITFVIYIAAMVLIGLAAYRSTNNFSDYILGGRSLGSFVTALSAGASDMSGWLLMGLPGAVYLSGLSESWIAIGLIVGAYLNWLFVAGRLRVQTEHNGNALTLPDYFTNRFEDNSRLLRIFSALVILVFFTIYCASGIVAGARLFESTFGLSYETALWAGAAATIAYTFIGGFLAVSWTDTVQASLMIFALILTPVIVMLATGGVEPTFTAIELKDATSFDMLKGASFIGVISLMAWGLGYFGQPHILARFMAADSVKSIPAARRISMTWMILCLGGAVAVGFFGIAYFQAHPEQAGAVSENPERVFIELAKILFNPWIAGVLLSAILAAVMSTLSCQLLVCSSALTEDFYKAFLRKGASQLELVWVGRAMVLLVAVIAIWLASNPENRVLGLVSYAWAGFGAAFGPLVLFSLLWKRMTRNGALAGMIVGAATVILWKNLLGWTGLYEIIPGFLFASVAIVVFSLLGKAPSTSMLKRFDDAEQEYREAHQGSAAPVTQR |
| References |
| External Links: |
|
| General Reference: |
PaperBLAST - Find papers about PA0783 and its homologs
|
