Identification |
Name: |
probable 3-hydroxyisobutyrate dehydrogenase |
Synonyms: |
Not Available |
Gene Name: |
Not Available |
Enzyme Class: |
Not Available |
Biological Properties |
General Function: |
pentose-phosphate shunt, oxidation-reduction process, valine metabolic process |
Specific Function: |
phosphogluconate dehydrogenase (decarboxylating) activity, 3-hydroxyisobutyrate dehydrogenase activity, NAD binding, oxidoreductase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, coenzyme binding |
Cellular Location: |
Cytoplasmic |
KEGG Pathways: |
|
KEGG Reactions: |
Not Available |
SMPDB Reactions: |
Not Available |
PseudoCyc/BioCyc Reactions: |
| ( S)-3-hydroxy-isobutanoate + NAD + → ( S)-methylmalonate-semialdehyde + NADH + H +ReactionCard |
|
Complex Reactions: |
Not Available |
Transports: |
Not Available |
Metabolites: |
Not Available |
GO Classification: |
Function |
---|
phosphogluconate dehydrogenase (decarboxylating) activity | 3-hydroxyisobutyrate dehydrogenase activity | NAD binding | oxidoreductase activity | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | coenzyme binding | Process |
---|
pentose-phosphate shunt | oxidation-reduction process | valine metabolic process |
|
Gene Properties |
Locus tag: |
PA0743 |
Strand: |
- |
Entrez Gene ID: |
882135 |
Accession: |
NP_249434.1 |
GI: |
15595940 |
Sequence start: |
810275 |
Sequence End: |
811171 |
Sequence Length: |
896 |
Gene Sequence: |
>PA0743
ATGAAACAGATCGCCTTCATCGGCCTCGGCCACATGGGCGCGCCGATGGCCACCAACCTGCTCAAGGCCGGCTACCTGCTGAACGTCTTCGACCTGGTGCAGAGCGCCGTCGACGGCCTGGTCGCCGCCGGCGCCAGCGCCGCCCGCAGCGCCCGCGACGCGGTGCAGGGCGCCGACGTGGTCATCAGCATGCTGCCGGCCAGCCAGCACGTCGAAGGCCTGTACCTCGACGACGATGGCCTGCTCGCGCACATCGCCCCCGGCACCCTGGTGCTGGAATGCTCGACCATCGCCCCGACCTCGGCGCGCAAGATCCACGCCGCCGCCCGCGAGCGCGGCCTGGCGATGCTCGACGCGCCGGTGTCCGGCGGCACTGCCGGCGCGGCAGCCGGCACCCTGACCTTCATGGTCGGCGGCGACGCCGAAGCCCTGGAGAAGGCCCGGCCGCTGTTCGAGGCCATGGGTCGCAACATCTTCCATGCCGGCCCCGACGGCGCCGGCCAGGTCGCCAAGGTGTGCAACAACCAACTCCTCGCGGTGCTGATGATCGGTACCGCAGAAGCCATGGCCCTGGGCGTGGCCAACGGCCTCGAGGCGAAGGTGCTGGCCGAGATCATGCGCCGCAGCTCCGGCGGCAACTGGGCGCTGGAAGTCTACAACCCCTGGCCGGGGGTGATGGAGAACGCTCCGGCGTCGCGCGACTACAGCGGCGGCTTCATGGCCCAGTTGATGGCCAAGGACCTCGGCCTGGCCCAGGAAGCCGCCCAGGCCAGCGCCAGCAGCACGCCGATGGGCAGCCTGGCGCTGAGCCTGTACCGCCTGTTGCTGAAGCAGGGCTATGCGGAGCGGGACTTTTCCGTGGTGCAGAAATTGTTCGATCCGACACAAGGCCAATAG |
Protein Properties |
Protein Residues: |
298 |
Protein Molecular Weight: |
30.8 kDa |
Protein Theoretical pI: |
5.31 |
Hydropathicity (GRAVY score): |
0.237 |
Charge at pH 7 (predicted): |
-4.86 |
Protein Sequence: |
>PA0743
MKQIAFIGLGHMGAPMATNLLKAGYLLNVFDLVQSAVDGLVAAGASAARSARDAVQGADVVISMLPASQHVEGLYLDDDGLLAHIAPGTLVLECSTIAPTSARKIHAAARERGLAMLDAPVSGGTAGAAAGTLTFMVGGDAEALEKARPLFEAMGRNIFHAGPDGAGQVAKVCNNQLLAVLMIGTAEAMALGVANGLEAKVLAEIMRRSSGGNWALEVYNPWPGVMENAPASRDYSGGFMAQLMAKDLGLAQEAAQASASSTPMGSLALSLYRLLLKQGYAERDFSVVQKLFDPTQGQ |
References |
External Links: |
|
General Reference: |
PaperBLAST - Find papers about PA0743 and its homologs
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