Identification
Name: probable 3-hydroxyisobutyrate dehydrogenase
Synonyms: Not Available
Gene Name: Not Available
Enzyme Class: Not Available
Biological Properties
General Function: pentose-phosphate shunt, oxidation-reduction process, valine metabolic process
Specific Function: phosphogluconate dehydrogenase (decarboxylating) activity, 3-hydroxyisobutyrate dehydrogenase activity, NAD binding, oxidoreductase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, coenzyme binding
Cellular Location: Cytoplasmic
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb
(S)-3-hydroxy-isobutanoate + NAD+ → (S)-methylmalonate-semialdehyde + NADH + H+
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites: Not Available
GO Classification:
Function
phosphogluconate dehydrogenase (decarboxylating) activity
3-hydroxyisobutyrate dehydrogenase activity
NAD binding
oxidoreductase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
coenzyme binding
Process
pentose-phosphate shunt
oxidation-reduction process
valine metabolic process
Gene Properties
Locus tag: PA0743
Strand: -
Entrez Gene ID: 882135
Accession: NP_249434.1
GI: 15595940
Sequence start: 810275
Sequence End: 811171
Sequence Length: 896
Gene Sequence:
>PA0743
ATGAAACAGATCGCCTTCATCGGCCTCGGCCACATGGGCGCGCCGATGGCCACCAACCTGCTCAAGGCCGGCTACCTGCTGAACGTCTTCGACCTGGTGCAGAGCGCCGTCGACGGCCTGGTCGCCGCCGGCGCCAGCGCCGCCCGCAGCGCCCGCGACGCGGTGCAGGGCGCCGACGTGGTCATCAGCATGCTGCCGGCCAGCCAGCACGTCGAAGGCCTGTACCTCGACGACGATGGCCTGCTCGCGCACATCGCCCCCGGCACCCTGGTGCTGGAATGCTCGACCATCGCCCCGACCTCGGCGCGCAAGATCCACGCCGCCGCCCGCGAGCGCGGCCTGGCGATGCTCGACGCGCCGGTGTCCGGCGGCACTGCCGGCGCGGCAGCCGGCACCCTGACCTTCATGGTCGGCGGCGACGCCGAAGCCCTGGAGAAGGCCCGGCCGCTGTTCGAGGCCATGGGTCGCAACATCTTCCATGCCGGCCCCGACGGCGCCGGCCAGGTCGCCAAGGTGTGCAACAACCAACTCCTCGCGGTGCTGATGATCGGTACCGCAGAAGCCATGGCCCTGGGCGTGGCCAACGGCCTCGAGGCGAAGGTGCTGGCCGAGATCATGCGCCGCAGCTCCGGCGGCAACTGGGCGCTGGAAGTCTACAACCCCTGGCCGGGGGTGATGGAGAACGCTCCGGCGTCGCGCGACTACAGCGGCGGCTTCATGGCCCAGTTGATGGCCAAGGACCTCGGCCTGGCCCAGGAAGCCGCCCAGGCCAGCGCCAGCAGCACGCCGATGGGCAGCCTGGCGCTGAGCCTGTACCGCCTGTTGCTGAAGCAGGGCTATGCGGAGCGGGACTTTTCCGTGGTGCAGAAATTGTTCGATCCGACACAAGGCCAATAG
Protein Properties
Protein Residues: 298
Protein Molecular Weight: 30.8 kDa
Protein Theoretical pI: 5.31
Hydropathicity (GRAVY score): 0.237
Charge at pH 7 (predicted): -4.86
Protein Sequence:
>PA0743
MKQIAFIGLGHMGAPMATNLLKAGYLLNVFDLVQSAVDGLVAAGASAARSARDAVQGADVVISMLPASQHVEGLYLDDDGLLAHIAPGTLVLECSTIAPTSARKIHAAARERGLAMLDAPVSGGTAGAAAGTLTFMVGGDAEALEKARPLFEAMGRNIFHAGPDGAGQVAKVCNNQLLAVLMIGTAEAMALGVANGLEAKVLAEIMRRSSGGNWALEVYNPWPGVMENAPASRDYSGGFMAQLMAKDLGLAQEAAQASASSTPMGSLALSLYRLLLKQGYAERDFSVVQKLFDPTQGQ
References
External Links:
Resource Link
Genome ID: PA0743
Entrez Gene ID: 882135
NCBI Protein ID: 15595940
General Reference: PaperBLAST - Find papers about PA0743 and its homologs