Identification
Name: Sensor protein creC
Synonyms: Not Available
Gene Name: creC
Enzyme Class:
Biological Properties
General Function: Signal transduction mechanisms
Specific Function: Member of the two-component regulatory system creC/creB involved in catabolic regulation. CreC may function as a membrane- associated protein kinase that phosphorylates creB in response to environmental signals. CreC can also phosphorylate phoB
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+protein L-histidineThumb+protein N-phospho-L-histidine
Adenosine triphosphate + protein L-histidine → ADP + protein N-phospho-L-histidine
ReactionCard
Complex Reactions:
Thumb+protein L-histidineThumb+protein N-phospho-L-histidine
Adenosine triphosphate + protein L-histidine → ADP + protein N-phospho-L-histidine
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
GO Classification:
Component
cell part
integral to membrane
intrinsic to membrane
membrane
membrane part
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
ATP binding
binding
catalytic activity
kinase activity
molecular transducer activity
nucleoside binding
protein histidine kinase activity
protein kinase activity
purine nucleoside binding
signal transducer activity
transferase activity
transferase activity, transferring phosphorus-containing groups
two-component sensor activity
Process
biological regulation
cellular metabolic process
metabolic process
peptidyl-histidine phosphorylation
phosphate metabolic process
phosphorus metabolic process
phosphorylation
protein amino acid phosphorylation
regulation of biological process
regulation of cellular process
signal transduction
Gene Properties
Locus tag: PA0464
Strand: +
Entrez Gene ID: 881807
Accession: NP_249155.1
GI: 15595661
Sequence start: 523943
Sequence End: 525367
Sequence Length: 1424
Gene Sequence:
>PA0464
ATGCCGCTCGGCGTTCGGATCTTCCTGGTCTACTTCCTGTTCGTCGGTCTCACCGGCTACTTCGTGCTGAGCACGGTGATGGACGAAGTGCGCCCCGGCGTGCGCCAGTCCACCGAGGAAACCCTGGTGGACACCGCCAACCTGCTCGCCGAGATCCTCCGCCAGGACGTGAAGAACGGCACCCTGGCACAGAGCGACCTGCCGGAGATGCTCGAGGACTACGGCAAGCGGGTGCCGCAGGCGGATATCTGGGGCTTGCGCAAGGAGGCGGTGAACCACCGCATCTACGTCACCGACGCCAGCGGCAAGGTGCTGCTGGACTCCGCCGGGGTGGCCGTCGGCCAGGACTATTCGCGCTGGAACGACGTCTACCTGACTCTCCGGGGCCAGTACGGCGCGCGCTCCAGCCGCGAAGACCCGGACGACCCGGATTCCTCGGTGATGTACGTGGCGGCGCCGATCAAGGATGGCGGGAAGATCATCGGGGTGGTTTCGGTGGCCAAGCCGAACAGCAGCCTGCAACCCTACATCGACCGCTCGCAGCGGCGCCTGGCCTGGCTCGGTGCCGGGCTGATCGCCCTCGGGCTGCTGGTCGGCGGCCTGCTCTCCTGGTGGCTCAGCGGCGCGCTGCGGCGCCTCACCCAGTACGCCCAGGCGGTCAGCGAGGGGCGCCGCGCCGAGCTGCCGCGCTATCGCGGCGGCGAGATGGCGCAACTGGCCGACGCGGTGGAACGCATGCGCACGCAACTGGAAGGCAAGGACTACGTCGAGCGCTACGTGCATACCCTGACCCACGAACTGAAGAGCCCATTGGCGGCGATCCGTGGCGCCGCCGAGTTGCTCGACGGCGAGATGCCGGCCGAGCAGCGGGCGCGCTTCGTCGGCAACATCGCCGGCGAGAGCGAGCGCCTGCAACAACTGATCGAGCGCCTGCTGAGCCTGGCCCAGGTGGAGCAGCGGCAAGGCCTGGAGGAGGTCGGCAAGGTCGACTTGCGGGAGATCGCCGCGTCCCTGCTGGAAGGCCAGGCGGCGCGTATCCAGCGCCAGCGATTGCGGGTGGAGAACCGCCTGGAAGGTCCCTGCGAGGTTCGCGGCGAGCAGTTCCTGCTGCGCCAGGCGCTGGCCAACCTGCTCGACAACGCCCTCGACTTCACCCCGCCCGGCGGCATCCTTCGCCTGCTCGCCGAGGCCGACGGCGAGGGTATCGCCTTGCGCCTGTTCAACCAGGGGCCGGCGATTCCCGACTACGCCCTGGCGCGCCTCACCGAACGCTTCTACTCGCTGCCGCGCCCGGCCAGCGGGCGCAAGAGCACCGGGCTGGGACTGAACTTCGTCGCCGAGGTGGCGCAACTGCATGGCGGCCGGTTGCAGGTCGGCAACCGCGACGACGGCGTCGAGGCGCTGCTCTGGCTGCCGCGCGGCTGA
Protein Properties
Protein Residues: 474
Protein Molecular Weight: 52.3 kDa
Protein Theoretical pI: 5.9
Hydropathicity (GRAVY score): -0.203
Charge at pH 7 (predicted): -3.04
Protein Sequence:
>PA0464
MPLGVRIFLVYFLFVGLTGYFVLSTVMDEVRPGVRQSTEETLVDTANLLAEILRQDVKNGTLAQSDLPEMLEDYGKRVPQADIWGLRKEAVNHRIYVTDASGKVLLDSAGVAVGQDYSRWNDVYLTLRGQYGARSSREDPDDPDSSVMYVAAPIKDGGKIIGVVSVAKPNSSLQPYIDRSQRRLAWLGAGLIALGLLVGGLLSWWLSGALRRLTQYAQAVSEGRRAELPRYRGGEMAQLADAVERMRTQLEGKDYVERYVHTLTHELKSPLAAIRGAAELLDGEMPAEQRARFVGNIAGESERLQQLIERLLSLAQVEQRQGLEEVGKVDLREIAASLLEGQAARIQRQRLRVENRLEGPCEVRGEQFLLRQALANLLDNALDFTPPGGILRLLAEADGEGIALRLFNQGPAIPDYALARLTERFYSLPRPASGRKSTGLGLNFVAEVAQLHGGRLQVGNRDDGVEALLWLPRG
References
External Links:
Resource Link
Genome ID: PA0464
Entrez Gene ID: 881807
NCBI Protein ID: 15595661
General Reference: PaperBLAST - Find papers about PA0464 and its homologs